2. Others Immunology/Inflammation Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite
  4. Cortodoxone-d5

Cortodoxone-d5  (Synonyms: 11-Deoxycortisol-d5; cortexolone-d5; Reichstein's substance S-d5)

Cat. No.: HY-77839S Purity: 99.90%
COA Handling Instructions

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Cortodoxone-d5 is the deuterium labeled Cortodoxone.

For research use only. We do not sell to patients.

Cortodoxone-d<sub>5</sub> Chemical Structure

Cortodoxone-d5 Chemical Structure

CAS No. : 1258063-56-7

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1 mg USD 842 In-stock
5 mg Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Cortodoxone-d5:

Cortodoxone-d5 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Cortodoxone-d5 is the deuterium labeled Cortodoxone.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cortodoxone-d5 Related Antibodies
Molecular Weight

351.49

Formula

C21H25D5O4
CAS No.
Unlabeled CAS

152-58-9
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2(O)C(CO)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C([2H])([2H])C3)=C([2H])C(C([2H])([2H])C4)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (142.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (142.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8450 mL 14.2252 mL 28.4503 mL
5 mM 0.5690 mL 2.8450 mL 5.6901 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.90%

COA (254 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.8450 mL 14.2252 mL 28.4503 mL 71.1258 mL
5 mM 0.5690 mL 2.8450 mL 5.6901 mL 14.2252 mL
10 mM 0.2845 mL 1.4225 mL 2.8450 mL 7.1126 mL
15 mM 0.1897 mL 0.9483 mL 1.8967 mL 4.7417 mL
20 mM 0.1423 mL 0.7113 mL 1.4225 mL 3.5563 mL
25 mM 0.1138 mL 0.5690 mL 1.1380 mL 2.8450 mL
30 mM 0.0948 mL 0.4742 mL 0.9483 mL 2.3709 mL
40 mM 0.0711 mL 0.3556 mL 0.7113 mL 1.7781 mL
50 mM 0.0569 mL 0.2845 mL 0.5690 mL 1.4225 mL
60 mM 0.0474 mL 0.2371 mL 0.4742 mL 1.1854 mL
80 mM 0.0356 mL 0.1778 mL 0.3556 mL 0.8891 mL
100 mM 0.0285 mL 0.1423 mL 0.2845 mL 0.7113 mL
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Cortodoxone-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cortodoxone-d51258063-56-711-Deoxycortisol-d5cortexolone-d5Reichstein's substance S-d5Isotope-Labeled CompoundsGlucocorticoid ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

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