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  4. Cu(II) protoporphyrin IX

Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair.

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Cu(II) protoporphyrin IX Chemical Structure

Cu(II) protoporphyrin IX Chemical Structure

CAS No. : 14494-37-2

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10 mg USD 550 In-stock
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Description

Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair[1][2][3].

Molecular Weight

624.19

Formula

C34H32CuN4O4
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

[O-]C(CCC(C1=CC(C(CCC([O-])=O)=C2C)=[N](C2=C3)[Cu+2]4([N-]5C3=C6C)[N-]1C7=CC(C(C=C)=C8C)=[N]4C8=CC5=C6C=C)=C7C)=O.[H+].[H+]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 18.73 mg/mL (30.01 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6021 mL 8.0104 mL 16.0208 mL
5 mM 0.3204 mL 1.6021 mL 3.2042 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 95.60%

COA (259 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6021 mL 8.0104 mL 16.0208 mL 40.0519 mL
5 mM 0.3204 mL 1.6021 mL 3.2042 mL 8.0104 mL
10 mM 0.1602 mL 0.8010 mL 1.6021 mL 4.0052 mL
15 mM 0.1068 mL 0.5340 mL 1.0681 mL 2.6701 mL
20 mM 0.0801 mL 0.4005 mL 0.8010 mL 2.0026 mL
25 mM 0.0641 mL 0.3204 mL 0.6408 mL 1.6021 mL
30 mM 0.0534 mL 0.2670 mL 0.5340 mL 1.3351 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cu(II) protoporphyrin IX Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cu(II) protoporphyrin IX14494-37-2OthersInhibitorinhibitorinhibit

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