2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. D-Histidine

D-Histidine is an enantiomer of L-histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.

For research use only. We do not sell to patients.

D-Histidine Chemical Structure

D-Histidine Chemical Structure

CAS No. : 351-50-8

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Based on 1 publication(s) in Google Scholar

Other Forms of D-Histidine:

D-Histidine Related Antibodies

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Description

D-Histidine is an enantiomer of L-histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport[1].

IC50 & Target

Human Endogenous Metabolite
Molecular Weight

155.15

Formula

C6H9N3O2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

OC([C@H](N)CC1=CN=CN1)=O
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 44.44 mg/mL (286.43 mM; ultrasonic and adjust pH to 7 with 1 M HCL)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4454 mL 32.2269 mL 64.4538 mL
5 mM 1.2891 mL 6.4454 mL 12.8908 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.98%

SDS (393 KB)

COA (248 KB) RP-HPLC (202 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.4454 mL 32.2269 mL 64.4538 mL 161.1344 mL
5 mM 1.2891 mL 6.4454 mL 12.8908 mL 32.2269 mL
10 mM 0.6445 mL 3.2227 mL 6.4454 mL 16.1134 mL
15 mM 0.4297 mL 2.1485 mL 4.2969 mL 10.7423 mL
20 mM 0.3223 mL 1.6113 mL 3.2227 mL 8.0567 mL
25 mM 0.2578 mL 1.2891 mL 2.5782 mL 6.4454 mL
30 mM 0.2148 mL 1.0742 mL 2.1485 mL 5.3711 mL
40 mM 0.1611 mL 0.8057 mL 1.6113 mL 4.0284 mL
50 mM 0.1289 mL 0.6445 mL 1.2891 mL 3.2227 mL
60 mM 0.1074 mL 0.5371 mL 1.0742 mL 2.6856 mL
80 mM 0.0806 mL 0.4028 mL 0.8057 mL 2.0142 mL
100 mM 0.0645 mL 0.3223 mL 0.6445 mL 1.6113 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-Histidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-Histidine351-50-8Mitochondrial MetabolismMitochondrialMetabolismEndogenousMetaboliteInhibitorinhibitorinhibit

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