2. Apoptosis PI3K/Akt/mTOR
  3. Apoptosis PI3K Akt
  4. DCZ3301

DCZ3301 is a potent aryl-guanidino inhibitor. DCZ3301 inhibits cell proliferation, induces G2/M cell cycle arrest and apoptosis. DCZ3301 inhibits the activation of the PI3K/AKT pathway by downregulating the protein expression of PI3K and phosphorylation of AKT. DCZ3301 can be used in research of cancer.

For research use only. We do not sell to patients.

DCZ3301 Chemical Structure

DCZ3301 Chemical Structure

CAS No. : 2136278-38-9

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Based on 1 publication(s) in Google Scholar

DCZ3301 Related Antibodies

Top Publications Citing Use of Products

View All PI3K Isoform Specific Products:

View All Isoforms
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

View All Akt Isoform Specific Products:

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Akt Akt1 Akt2 Akt3

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Description

DCZ3301 is a potent aryl-guanidino inhibitor. DCZ3301 inhibits cell proliferation, induces G2/M cell cycle arrest and apoptosis. DCZ3301 inhibits the activation of the PI3K/AKT pathway by downregulating the protein expression of PI3K and phosphorylation of AKT. DCZ3301 can be used in research of cancer[1].

Molecular Weight

464.83

Formula

C20H16ClF3N6O2
CAS No.
SMILES

O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=N)N=C2)=C1)NC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DCZ3301 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DCZ33012136278-38-9DCZ 3301DCZ-3301ApoptosisPI3KAktPhosphoinositide 3-kinasePKBProtein kinase Baryl-guanidinoproliferationG2/McancerT-cell leukemialymphoma cellsInhibitorinhibitorinhibit

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