2. Others Antibody-drug Conjugate/ADC Related
  3. Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)
  4. Deferoxamine-DBCO

Deferoxamine-DBCO  (Synonyms: DFO-DBCO)

Cat. No.: HY-158067 Purity: 89.40%
COA Handling Instructions

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Deferoxamine-DBCOis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DFO derivative used for tumor pre-targeting. Deferoxamine-DBCO can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

Deferoxamine-DBCO Chemical Structure

Deferoxamine-DBCO Chemical Structure

CAS No. : 2359695-48-8

Size Price Stock Quantity
5 mg USD 210 In-stock
10 mg USD 340 In-stock
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Based on 1 publication(s) in Google Scholar

Deferoxamine-DBCO Related Antibodies

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Description

Deferoxamine-DBCOis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DFO derivative used for tumor pre-targeting. Deferoxamine-DBCO can be used for conjugation of peptides and radionuclides.

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

848.00

Formula

C44H61N7O10
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

CC(N(CCCCCNC(CCC(N(CCCCCNC(CCC(N(CCCCCNC(CCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O)=O)O)=O)=O)O)=O)=O)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (117.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1792 mL 5.8962 mL 11.7925 mL
5 mM 0.2358 mL 1.1792 mL 2.3585 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 89.40%

COA (242 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1792 mL 5.8962 mL 11.7925 mL 29.4811 mL
5 mM 0.2358 mL 1.1792 mL 2.3585 mL 5.8962 mL
10 mM 0.1179 mL 0.5896 mL 1.1792 mL 2.9481 mL
15 mM 0.0786 mL 0.3931 mL 0.7862 mL 1.9654 mL
20 mM 0.0590 mL 0.2948 mL 0.5896 mL 1.4741 mL
25 mM 0.0472 mL 0.2358 mL 0.4717 mL 1.1792 mL
30 mM 0.0393 mL 0.1965 mL 0.3931 mL 0.9827 mL
40 mM 0.0295 mL 0.1474 mL 0.2948 mL 0.7370 mL
50 mM 0.0236 mL 0.1179 mL 0.2358 mL 0.5896 mL
60 mM 0.0197 mL 0.0983 mL 0.1965 mL 0.4914 mL
80 mM 0.0147 mL 0.0737 mL 0.1474 mL 0.3685 mL
100 mM 0.0118 mL 0.0590 mL 0.1179 mL 0.2948 mL
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Deferoxamine-DBCO Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deferoxamine-DBCO2359695-48-8DFO-DBCOBiochemical Assay ReagentsRadionuclide-Drug Conjugates (RDCs)Inhibitorinhibitorinhibit

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