1. Cell Cycle/DNA Damage
  2. Endonuclease
  3. Deoxyribonuclease II

Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research.

For research use only. We do not sell to patients.

Deoxyribonuclease II Chemical Structure

Deoxyribonuclease II Chemical Structure

CAS No. : 9025-64-3

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Description

Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research[1].

In Vitro

Product Information
Molecular Weight: 38.0 kDa
Optimal pH: 4.5-5.0
Activators: Cysteine, EDTA
Inhibitors: Actinomycin D, iodoacetate, N-bromosuccinimide, H2O2, divalent cations (such as zinc and copper), sulfate, NaCl (above 250 mM), DNA (above 4 mg/mL)
Instructions
Soluble in pure water (1 mg/mL), fresh preparation is recommended. Or dissolve in buffer according to specific experimental references.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

[Deoxyribonuclease II]

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O : ≥ 5 mg/mL

*"≥" means soluble, but saturation unknown.

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Product Name:
Deoxyribonuclease II
Cat. No.:
HY-P2863
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