1. Vitamin D Related/Nuclear Receptor
  2. Estrogen Receptor/ERR
  3. Diethylstilbestrol-d8

Diethylstilbestrol-d8 is the deuterium labeled Diethylstilbestrol. Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders[1][2].

For research use only. We do not sell to patients.

Diethylstilbestrol-d<sub>8</sub> Chemical Structure

Diethylstilbestrol-d8 Chemical Structure

CAS No. : 91318-10-4

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5 mg USD 250 In-stock
10 mg USD 400 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Diethylstilbestrol-d8 is the deuterium labeled Diethylstilbestrol. Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

276.40

Formula

C18H12D8O2

CAS No.
Unlabeled CAS

56-53-1

Appearance

Solid

Color

White to off-white

SMILES

CC([2H])([2H])/C(C1=CC([2H])=C(C([2H])=C1)O)=C(C2=CC([2H])=C(C([2H])=C2)O)/C([2H])([2H])C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (180.90 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6179 mL 18.0897 mL 36.1795 mL
5 mM 0.7236 mL 3.6179 mL 7.2359 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6179 mL 18.0897 mL 36.1795 mL 90.4486 mL
5 mM 0.7236 mL 3.6179 mL 7.2359 mL 18.0897 mL
10 mM 0.3618 mL 1.8090 mL 3.6179 mL 9.0449 mL
15 mM 0.2412 mL 1.2060 mL 2.4120 mL 6.0299 mL
20 mM 0.1809 mL 0.9045 mL 1.8090 mL 4.5224 mL
25 mM 0.1447 mL 0.7236 mL 1.4472 mL 3.6179 mL
30 mM 0.1206 mL 0.6030 mL 1.2060 mL 3.0150 mL
40 mM 0.0904 mL 0.4522 mL 0.9045 mL 2.2612 mL
50 mM 0.0724 mL 0.3618 mL 0.7236 mL 1.8090 mL
60 mM 0.0603 mL 0.3015 mL 0.6030 mL 1.5075 mL
80 mM 0.0452 mL 0.2261 mL 0.4522 mL 1.1306 mL
100 mM 0.0362 mL 0.1809 mL 0.3618 mL 0.9045 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Diethylstilbestrol-d8
Cat. No.:
HY-14598S
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