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  3. Ditiocarb

Ditiocarb  (Synonyms: Diethyldithiocarbamic acid)

Cat. No.: HY-126363
Handling Instructions

Ditiocarb (Diethyldithiocarbamic acid) is an accelerator of the rate of copper cementation. Ditiocarb (Diethyldithiocarbamic acid) reduces the incidence of HIV infection, and also enhances adjuvant immunoresearch of high risk breast cancer.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Ditiocarb sodium) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Ditiocarb Chemical Structure

Ditiocarb Chemical Structure

CAS No. : 147-84-2

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Description

Ditiocarb (Diethyldithiocarbamic acid) is an accelerator of the rate of copper cementation. Ditiocarb (Diethyldithiocarbamic acid) reduces the incidence of HIV infection, and also enhances adjuvant immunoresearch of high risk breast cancer[1][2][3].

Cellular Effect
Cell Line Type Value Description References
CEM-SS IC50
> 100 μM
Compound: dithiocarbamate
Antiviral activity against HIV-1 in CEM-SS cells using XXT assay
Antiviral activity against HIV-1 in CEM-SS cells using XXT assay
[PMID: 9207937]
CEM-SS IC50
> 100 μM
Compound: dithiocarbamate
Antiviral activity against HIV-1ADA in CEM-SS cells using monocyte/macrophage cultures
Antiviral activity against HIV-1ADA in CEM-SS cells using monocyte/macrophage cultures
[PMID: 9207937]
In Vitro

Ditiocarb reacts with the Cu2+ solution giving a complex of copper diethyldithiocarbamate, which enhances the rate of cementation[1]. Ditiocarb is an agent with strong antioxidant capacity and chelating activities[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ditiocarb improves the depressed immune responses of newborn and aged mice. Ditiocarb prevents cisplatin nephrotoxicity in animals without reducing the antitumor activity.
In that AIDS model, Ditiocarb reduces lymphadenopathy and hypergammaglobulinemia, restores immunocompetence, and prolongs survival[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

149.28

Formula

C5H11NS2

CAS No.
SMILES

SC(N(CC)CC)=S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Ditiocarb Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ditiocarb
Cat. No.:
HY-126363
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