DL-Methionine-d₄

Name: DL-Methionine-d 4
Brand: MedChemExpress
SKU: HY-N0325S4
Rating: 4.5 (1 reviews)

Cat. No.: HY-N0325S4 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DL-Methionine-d₄ is the deuterium labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants[1][2][3].

For research use only. We do not sell to patients.

DL-Methionine-d<sub>4</sub> Chemical Structure

DL-Methionine-d₄ Chemical Structure

CAS No. : 93709-61-6

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DL-Methionine-d₄:

DL-Methionine Get quote

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Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

153.24

Formula

C₅H₇D₄NO₂S

CAS No.

93709-61-6

Unlabeled CAS

59-51-8

Appearance

Solid

Color

White to off-white

SMILES

OC(C(N)C([2H])([2H])C([2H])([2H])SC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 25 mg/mL (163.14 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.5257 mL	32.6286 mL	65.2571 mL
5 mM	1.3051 mL	6.5257 mL	13.0514 mL
10 mM	0.6526 mL	3.2629 mL	6.5257 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (249 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. K. evans, et al. Effects of amino acids on the reproduction of Heterodera rostochiensis. Nematologica, 1971, 17(4), 495-500.

[3]. Swennen Q, et al. Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens. Br J Nutr. 2011 Dec;106(12):1845-54. [Content Brief]

[4]. Garlich JD. Response of broilers to DL-methionine hydroxy analog free acid, DL-methionine, and L-methionine. Poult Sci. 1985 Aug;64(8):1541-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.5257 mL	32.6286 mL	65.2571 mL	163.1428 mL
	5 mM	1.3051 mL	6.5257 mL	13.0514 mL	32.6286 mL
	10 mM	0.6526 mL	3.2629 mL	6.5257 mL	16.3143 mL
	15 mM	0.4350 mL	2.1752 mL	4.3505 mL	10.8762 mL
	20 mM	0.3263 mL	1.6314 mL	3.2629 mL	8.1571 mL
	25 mM	0.2610 mL	1.3051 mL	2.6103 mL	6.5257 mL
	30 mM	0.2175 mL	1.0876 mL	2.1752 mL	5.4381 mL
	40 mM	0.1631 mL	0.8157 mL	1.6314 mL	4.0786 mL
	50 mM	0.1305 mL	0.6526 mL	1.3051 mL	3.2629 mL
	60 mM	0.1088 mL	0.5438 mL	1.0876 mL	2.7190 mL
	80 mM	0.0816 mL	0.4079 mL	0.8157 mL	2.0393 mL
	100 mM	0.0653 mL	0.3263 mL	0.6526 mL	1.6314 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.