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  3. Parasite
  4. DL-Methionine

DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants.

For research use only. We do not sell to patients.

DL-Methionine Chemical Structure

DL-Methionine Chemical Structure

CAS No. : 59-51-8

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Based on 1 publication(s) in Google Scholar

Other Forms of DL-Methionine:

DL-Methionine Related Antibodies

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Description

DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants[1][2][3].

IC50 & Target

H. rostochiensis[1]
In Vitro

The impact of DL-Methionine supplementation on animal performance interacts strongly with the crude protein (CP) content of the diet. Supplementation of DLM to a 20% crude protein diet for broilers reduces their abdominal fat weight, whereas this is not the case when the diet contained 23% CP. Breast meat yield is increased and abdominal fat content is decreased with increasing DL-Methionine supplementation, and this response is more pronounced in chickens reared on a diet with a lower protein level (20.5% CP) compared with a higher protein level (26%)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DL-Methionine Related Antibodies
In Vivo

DL-methionine significantly decreases the numbers of males, females, cysts and eggs of H. rostochiensis on potato plants. DL-methionine kills almost all the nematodes when applied 3 days after inoculation, and DL-methionine does not affect plant growth adversely[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

149.21

Formula

C5H11NO2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC(CCSC)C(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

1M HCl : 100 mg/mL (670.20 mM; ultrasonic and adjust pH to 1 with HCl)

H2O : 33.33 mg/mL (223.38 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.7020 mL 33.5098 mL 67.0196 mL
5 mM 1.3404 mL 6.7020 mL 13.4039 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 10 mg/mL (67.02 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (244 KB) HNMR (231 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / 1M HCl 1 mM 6.7020 mL 33.5098 mL 67.0196 mL 167.5491 mL
5 mM 1.3404 mL 6.7020 mL 13.4039 mL 33.5098 mL
10 mM 0.6702 mL 3.3510 mL 6.7020 mL 16.7549 mL
15 mM 0.4468 mL 2.2340 mL 4.4680 mL 11.1699 mL
20 mM 0.3351 mL 1.6755 mL 3.3510 mL 8.3775 mL
25 mM 0.2681 mL 1.3404 mL 2.6808 mL 6.7020 mL
30 mM 0.2234 mL 1.1170 mL 2.2340 mL 5.5850 mL
40 mM 0.1675 mL 0.8377 mL 1.6755 mL 4.1887 mL
50 mM 0.1340 mL 0.6702 mL 1.3404 mL 3.3510 mL
60 mM 0.1117 mL 0.5585 mL 1.1170 mL 2.7925 mL
80 mM 0.0838 mL 0.4189 mL 0.8377 mL 2.0944 mL
100 mM 0.0670 mL 0.3351 mL 0.6702 mL 1.6755 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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DL-Methionine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-Methionine59-51-8ParasiteEssentialaminoacidsulfuroxidativestressH. rostochiensisnaturalfeedInhibitorinhibitorinhibit

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