2. PROTAC
  3. Ligands for E3 Ligase
  4. E3 ligase Ligand 32

E3 ligase Ligand 32 (First product in Example 52) is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 32 can be connected to the ligand for protein by a linker to form PROTACs and can be used for the synthesis of PROTAC SMARCA2/4-degrader-29 (HY-162743).

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E3 ligase Ligand 32 Chemical Structure

E3 ligase Ligand 32 Chemical Structure

CAS No. : 2300099-98-1

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E3 ligase Ligand 32 Related Antibodies

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Description

E3 ligase Ligand 32 (First product in Example 52) is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 32 can be connected to the ligand for protein by a linker to form PROTACs and can be used for the synthesis of PROTAC SMARCA2/4-degrader-29 (HY-162743)[1].

Molecular Weight

338.16

Formula

C13H12BrN3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NC(=O)C(CC1)N2C3=C(C=C(Br)C=C3)N(C)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.95%

COA (256 KB) HNMR (116 KB) RP-HPLC (224 KB) LCMS (98 KB)

Handling Instructions (2659 KB)
References
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E3 ligase Ligand 32 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E3 ligase Ligand 322300099-98-1Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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