2. Neuronal Signaling
  3. Serotonin Transporter
  4. Edivoxetine hydrochloride

Edivoxetine hydrochloride  (Synonyms: LY 2216684 hydrochloride)

Cat. No.: HY-15413A Purity: 99.85%
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Edivoxetine (hydrochloride) is a selective and potent norepinephrine reuptake inhibitor (NERI) being used in depressive disorder or attention-deficit/hyperactivity disorder.

For research use only. We do not sell to patients.

Edivoxetine hydrochloride Chemical Structure

Edivoxetine hydrochloride Chemical Structure

CAS No. : 1194374-05-4

Size Price Stock Quantity
5 mg USD 240 In-stock
10 mg USD 385 In-stock
25 mg USD 770 In-stock
50 mg USD 1230 In-stock
100 mg USD 1950 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Edivoxetine hydrochloride:

Edivoxetine hydrochloride Related Antibodies

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Description

Edivoxetine (hydrochloride) is a selective and potent norepinephrine reuptake inhibitor (NERI) being used in depressive disorder or attention-deficit/hyperactivity disorder.

Clinical Trial
Molecular Weight

375.86

Formula

C18H27ClFNO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC(C=CC(F)=C1)=C1C[C@@](C2CCOCC2)([C@]3([H])CNCCO3)O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (332.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6606 mL 13.3028 mL 26.6057 mL
5 mM 0.5321 mL 2.6606 mL 5.3211 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6606 mL 13.3028 mL 26.6057 mL 66.5141 mL
5 mM 0.5321 mL 2.6606 mL 5.3211 mL 13.3028 mL
10 mM 0.2661 mL 1.3303 mL 2.6606 mL 6.6514 mL
15 mM 0.1774 mL 0.8869 mL 1.7737 mL 4.4343 mL
20 mM 0.1330 mL 0.6651 mL 1.3303 mL 3.3257 mL
25 mM 0.1064 mL 0.5321 mL 1.0642 mL 2.6606 mL
30 mM 0.0887 mL 0.4434 mL 0.8869 mL 2.2171 mL
40 mM 0.0665 mL 0.3326 mL 0.6651 mL 1.6629 mL
50 mM 0.0532 mL 0.2661 mL 0.5321 mL 1.3303 mL
60 mM 0.0443 mL 0.2217 mL 0.4434 mL 1.1086 mL
80 mM 0.0333 mL 0.1663 mL 0.3326 mL 0.8314 mL
100 mM 0.0266 mL 0.1330 mL 0.2661 mL 0.6651 mL
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Edivoxetine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Edivoxetine1194374-05-4LY 2216684LY2216684LY-2216684Serotonin Transporter5-HTTSERTSLC6A4Inhibitorinhibitorinhibit

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