1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Apoptosis
  2. EGFR Apoptosis
  3. EGFR-IN-105

EGFR-IN-105 (Compound 5b) is an EGFR2 inhibitor with an IC50 value of 0.68 μM. EGFR-IN-105 exhibits anticancer activity and can induce apoptosis in cancer cells, which is used in the research of pancreatic cancer.

For research use only. We do not sell to patients.

EGFR-IN-105 Chemical Structure

EGFR-IN-105 Chemical Structure

CAS No. : 831244-98-5

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Description

EGFR-IN-105 (Compound 5b) is an EGFR2 inhibitor with an IC50 value of 0.68 μM. EGFR-IN-105 exhibits anticancer activity and can induce apoptosis in cancer cells, which is used in the research of pancreatic cancer[1].

IC50 & Target

ErbB2

0.68 μM ()

Molecular Weight

374.54

Formula

C20H30N4OS

CAS No.
SMILES

O=C(NC1=C(C#N)C(CCC(C(C)(C)C)C2)=C2S1)CN3CCN(C)CC3

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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EGFR-IN-105
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HY-161320
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