1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Ethylenethiourea

Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active.

For research use only. We do not sell to patients.

Ethylenethiourea Chemical Structure

Ethylenethiourea Chemical Structure

CAS No. : 96-45-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 27 In-stock
Solution
10 mM * 1 mL in DMSO USD 28 In-stock
Solid
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Description

Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active[1][2].

In Vitro

Ethylenethiourea is stable at elevated temperature over a wide pH range[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ethylenethiourea (10-80 mg/kg; p.o.) is teratogenic in rats[1].
Ethylenethiourea (5-500 ppm; in the diet; 12 month) induces thyroid carcinomas in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Virgin Wistar female rats[1]
Dosage: 0, 5, 10, 20, 40 or 80 mg/kg
Administration: Oral administration, from 21-42 days before conception to pregnancy day 15, and on days 6-15 or 7-20 of pregnancy
Result: Induced meningoencephalocele, meningorrhagia, meningorrhea, hydrocephalus, obliterated neural canal, abnormal pelvic limb posture with equinovarus, and short or kinky tail after 10 mg/kg or more.
Molecular Weight

102.16

Formula

C3H6N2S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C1NCCN1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (244.71 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.7886 mL 48.9428 mL 97.8857 mL
5 mM 1.9577 mL 9.7886 mL 19.5771 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 9.7886 mL 48.9428 mL 97.8857 mL 244.7142 mL
5 mM 1.9577 mL 9.7886 mL 19.5771 mL 48.9428 mL
10 mM 0.9789 mL 4.8943 mL 9.7886 mL 24.4714 mL
15 mM 0.6526 mL 3.2629 mL 6.5257 mL 16.3143 mL
20 mM 0.4894 mL 2.4471 mL 4.8943 mL 12.2357 mL
25 mM 0.3915 mL 1.9577 mL 3.9154 mL 9.7886 mL
30 mM 0.3263 mL 1.6314 mL 3.2629 mL 8.1571 mL
40 mM 0.2447 mL 1.2236 mL 2.4471 mL 6.1179 mL
50 mM 0.1958 mL 0.9789 mL 1.9577 mL 4.8943 mL
60 mM 0.1631 mL 0.8157 mL 1.6314 mL 4.0786 mL
80 mM 0.1224 mL 0.6118 mL 1.2236 mL 3.0589 mL
100 mM 0.0979 mL 0.4894 mL 0.9789 mL 2.4471 mL
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Product Name:
Ethylenethiourea
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