2. Immunology/Inflammation
  3. FAP
  4. FAP-IN-2 TFA

FAP-IN-2 TFA is a 99mTc-labeled isonitrile-containing FAP inhibitor derivative that can be used for tumor imaging.

For research use only. We do not sell to patients.

FAP-IN-2 TFA Chemical Structure

FAP-IN-2 TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 140 In-stock
5 mg USD 300 In-stock
10 mg USD 450 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of FAP-IN-2 TFA:

FAP-IN-2 TFA Related Antibodies

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Description

FAP-IN-2 TFA is a 99mTc-labeled isonitrile-containing FAP inhibitor derivative that can be used for tumor imaging[1].

Molecular Weight

600.54

Formula

C26H29F5N6O5
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCN4CCNCC4)C=C3)=O.O=C(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (416.29 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 125 mg/mL (208.15 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6652 mL 8.3258 mL 16.6517 mL
5 mM 0.3330 mL 1.6652 mL 3.3303 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.92%

COA (249 KB) HNMR (308 KB) LCMS (95 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.6652 mL 8.3258 mL 16.6517 mL 41.6292 mL
5 mM 0.3330 mL 1.6652 mL 3.3303 mL 8.3258 mL
10 mM 0.1665 mL 0.8326 mL 1.6652 mL 4.1629 mL
15 mM 0.1110 mL 0.5551 mL 1.1101 mL 2.7753 mL
20 mM 0.0833 mL 0.4163 mL 0.8326 mL 2.0815 mL
25 mM 0.0666 mL 0.3330 mL 0.6661 mL 1.6652 mL
30 mM 0.0555 mL 0.2775 mL 0.5551 mL 1.3876 mL
40 mM 0.0416 mL 0.2081 mL 0.4163 mL 1.0407 mL
50 mM 0.0333 mL 0.1665 mL 0.3330 mL 0.8326 mL
60 mM 0.0278 mL 0.1388 mL 0.2775 mL 0.6938 mL
80 mM 0.0208 mL 0.1041 mL 0.2081 mL 0.5204 mL
100 mM 0.0167 mL 0.0833 mL 0.1665 mL 0.4163 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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FAP-IN-2 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAP-IN-2FAPFibroblast activation proteinInhibitorinhibitorinhibit

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