1. Immunology/Inflammation
  2. FAP
  3. FAPI-mFS

FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

FAPI-mFS Chemical Structure

FAPI-mFS Chemical Structure

CAS No. : 3023869-94-2

Size Price Stock Quantity
1 mg USD 900 In-stock
5 mg USD 2300 In-stock
10 mg USD 3450 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu[1].

Molecular Weight

1203.25

Formula

C53H69F3N12O15S

CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (83.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8311 mL 4.1554 mL 8.3108 mL
5 mM 0.1662 mL 0.8311 mL 1.6622 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8311 mL 4.1554 mL 8.3108 mL 20.7771 mL
5 mM 0.1662 mL 0.8311 mL 1.6622 mL 4.1554 mL
10 mM 0.0831 mL 0.4155 mL 0.8311 mL 2.0777 mL
15 mM 0.0554 mL 0.2770 mL 0.5541 mL 1.3851 mL
20 mM 0.0416 mL 0.2078 mL 0.4155 mL 1.0389 mL
25 mM 0.0332 mL 0.1662 mL 0.3324 mL 0.8311 mL
30 mM 0.0277 mL 0.1385 mL 0.2770 mL 0.6926 mL
40 mM 0.0208 mL 0.1039 mL 0.2078 mL 0.5194 mL
50 mM 0.0166 mL 0.0831 mL 0.1662 mL 0.4155 mL
60 mM 0.0139 mL 0.0693 mL 0.1385 mL 0.3463 mL
80 mM 0.0104 mL 0.0519 mL 0.1039 mL 0.2597 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FAPI-mFS
Cat. No.:
HY-164725
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