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  4. Fenipentol

Fenipentol  (Synonyms: 1-Phenyl-1-pentanol)

Cat. No.: HY-B1273 Purity: 98.28%
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Fenipentol (1-Phenyl-1-pentanol), a synthetic derivative of an ingredient of Curcuma longa that is used as a condiment and dye. Fenipentol is also an orally active choleretic agent that plays an important role in release of secretin, gastrin, and pancreatic secretion of bicarbonate and protein.

For research use only. We do not sell to patients.

Fenipentol Chemical Structure

Fenipentol Chemical Structure

CAS No. : 583-03-9

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Liquid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Fenipentol Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fenipentol (1-Phenyl-1-pentanol), a synthetic derivative of an ingredient of Curcuma longa that is used as a condiment and dye. Fenipentol is also an orally active choleretic agent that plays an important role in release of secretin, gastrin, and pancreatic secretion of bicarbonate and protein[1][2][3].

In Vivo

Fenipentol (PHP) (50-200 mg/kg; p.o. and intraduodenal administration) increases the secretory volume of pancreatic juice and the output of protein in rats[2].
Fenipentol (50-200 mg/kg for i.p. and 5-10 mg/kg for i.v.) considerably increases biliary secretion in rats[2].
Fenipentol (25-200 mg/kg; intraduodenal administration) stimulates the pancreatic secretion in the canine[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

164.25

Formula

C11H16O
CAS No.
Appearance

Liquid (Density: 0.96 g/cm3)

Color

Colorless to light yellow

SMILES

OC(CCCC)C1=CC=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (608.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0884 mL 30.4418 mL 60.8835 mL
5 mM 1.2177 mL 6.0884 mL 12.1767 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (15.22 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (15.22 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.0884 mL 30.4418 mL 60.8835 mL 152.2089 mL
5 mM 1.2177 mL 6.0884 mL 12.1767 mL 30.4418 mL
10 mM 0.6088 mL 3.0442 mL 6.0884 mL 15.2209 mL
15 mM 0.4059 mL 2.0295 mL 4.0589 mL 10.1473 mL
20 mM 0.3044 mL 1.5221 mL 3.0442 mL 7.6104 mL
25 mM 0.2435 mL 1.2177 mL 2.4353 mL 6.0884 mL
30 mM 0.2029 mL 1.0147 mL 2.0295 mL 5.0736 mL
40 mM 0.1522 mL 0.7610 mL 1.5221 mL 3.8052 mL
50 mM 0.1218 mL 0.6088 mL 1.2177 mL 3.0442 mL
60 mM 0.1015 mL 0.5074 mL 1.0147 mL 2.5368 mL
80 mM 0.0761 mL 0.3805 mL 0.7610 mL 1.9026 mL
100 mM 0.0609 mL 0.3044 mL 0.6088 mL 1.5221 mL
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Fenipentol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fenipentol583-03-91-Phenyl-1-pentanolFluorescent DyecholereticInhibitorinhibitorinhibit

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