Flomoxef sodium

Name: Flomoxef sodium
Brand: MedChemExpress
SKU: HY-B0706A
Rating: 4.5 (1 reviews)

Cat. No.: HY-B0706A Purity: 99.33%: FAQs
Data Sheet SDS COA Handling Instructions

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Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria.

For research use only. We do not sell to patients.

Flomoxef sodium Chemical Structure

CAS No. : 92823-03-5

Size	Price	Stock	Quantity
5 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 210	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Flomoxef sodium:

Flomoxef Get quote
Flomoxef sodium (Standard) Get quote

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Biological Activity
Purity & Documentation
References
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Description

Flomoxef sodium is a oxacephem group antibiotic, with excellent activity against various Gram-positive bacteria^[1]^[2].

IC₅₀ & Target

β-lactam

Clinical Trial

Molecular Weight

518.45

Formula

C₁₅H₁₇F₂N₆NaO₇S₂

CAS No.

92823-03-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(C(N12)=C(CSC3=NN=NN3CCO)CO[C@]2([H])[C@](OC)(NC(CSC(F)F)=O)C1=O)O[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (482.21 mM; Need ultrasonic)

DMSO : ≥ 250 mg/mL (482.21 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9288 mL	9.6441 mL	19.2883 mL
5 mM	0.3858 mL	1.9288 mL	3.8577 mL
10 mM	0.1929 mL	0.9644 mL	1.9288 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (4.01 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (4.01 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.08 mg/mL (4.01 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (192.88 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.33%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (254 KB) HNMR (274 KB) RP-HPLC (235 KB) MS (178 KB)

Handling Instructions (2659 KB)

References

[1]. Yazawa K, et al. In-vitro activity of flomoxef, a new oxacephem group antibiotic, against Nocardia in comparison with other cephalosporins. J Antimicrob Chemother. 1989 Dec;24(6):921-5. [Content Brief]

[2]. Simon C, et al. In vitro activity of flomoxef in comparison to other cephalosporins. Infection. 1988 Mar-Apr;16(2):131-4. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	1.9288 mL	9.6441 mL	19.2883 mL	48.2207 mL
	5 mM	0.3858 mL	1.9288 mL	3.8577 mL	9.6441 mL
	10 mM	0.1929 mL	0.9644 mL	1.9288 mL	4.8221 mL
	15 mM	0.1286 mL	0.6429 mL	1.2859 mL	3.2147 mL
	20 mM	0.0964 mL	0.4822 mL	0.9644 mL	2.4110 mL
	25 mM	0.0772 mL	0.3858 mL	0.7715 mL	1.9288 mL
	30 mM	0.0643 mL	0.3215 mL	0.6429 mL	1.6074 mL
	40 mM	0.0482 mL	0.2411 mL	0.4822 mL	1.2055 mL
	50 mM	0.0386 mL	0.1929 mL	0.3858 mL	0.9644 mL
	60 mM	0.0321 mL	0.1607 mL	0.3215 mL	0.8037 mL
	80 mM	0.0241 mL	0.1206 mL	0.2411 mL	0.6028 mL
	100 mM	0.0193 mL	0.0964 mL	0.1929 mL	0.4822 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Flomoxef sodium Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flomoxef92823-03-5BacterialAntibioticInhibitorinhibitorinhibit

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Flomoxef sodium

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Other Forms of Flomoxef sodium:

Flomoxef sodium Related Antibodies

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•Related Screening Libraries:

•Related Small Molecules:

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View All Antibiotic Isoform Specific Products:

Biological Activity

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References

Customer Review

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Complete Stock Solution Preparation Table

Flomoxef sodium Related Classifications

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