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  3. Amino Acid Derivatives
  4. Fmoc-α-Me-Leu-OH

Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity.

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Fmoc-α-Me-Leu-OH Chemical Structure

Fmoc-α-Me-Leu-OH Chemical Structure

CAS No. : 312624-65-0

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Based on 1 publication(s) in Google Scholar

Fmoc-α-Me-Leu-OH Related Antibodies

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Description

Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity[1].

Molecular Weight

367.44

Formula

C22H25NO4
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (272.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7215 mL 13.6077 mL 27.2153 mL
5 mM 0.5443 mL 2.7215 mL 5.4431 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.50% ee.: 99.92%

SDS (394 KB)

COA (253 KB) HNMR (123 KB) RP-HPLC (265 KB) NP-HPLC (310 KB) LCMS (97 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7215 mL 13.6077 mL 27.2153 mL 68.0383 mL
5 mM 0.5443 mL 2.7215 mL 5.4431 mL 13.6077 mL
10 mM 0.2722 mL 1.3608 mL 2.7215 mL 6.8038 mL
15 mM 0.1814 mL 0.9072 mL 1.8144 mL 4.5359 mL
20 mM 0.1361 mL 0.6804 mL 1.3608 mL 3.4019 mL
25 mM 0.1089 mL 0.5443 mL 1.0886 mL 2.7215 mL
30 mM 0.0907 mL 0.4536 mL 0.9072 mL 2.2679 mL
40 mM 0.0680 mL 0.3402 mL 0.6804 mL 1.7010 mL
50 mM 0.0544 mL 0.2722 mL 0.5443 mL 1.3608 mL
60 mM 0.0454 mL 0.2268 mL 0.4536 mL 1.1340 mL
80 mM 0.0340 mL 0.1701 mL 0.3402 mL 0.8505 mL
100 mM 0.0272 mL 0.1361 mL 0.2722 mL 0.6804 mL
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Fmoc-α-Me-Leu-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-α-Me-Leu-OH312624-65-0Amino Acid DerivativesProtecting grouppeptide synthesisderivativeleucineInhibitorinhibitorinhibit

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