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FPH1(BRD-6125) increases the number and activity of primary human hepatocytes in vitro and promotes the differentiation of iPS cells towards a hepatic lineage.

For research use only. We do not sell to patients.

FPH1 Chemical Structure

FPH1 Chemical Structure

CAS No. : 708219-39-0

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1 mg USD 28 In-stock
5 mg USD 70 In-stock
10 mg USD 120 In-stock
25 mg USD 240 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

FPH1(BRD-6125) increases the number and activity of primary human hepatocytes in vitro and promotes the differentiation of iPS cells towards a hepatic lineage[1].

Molecular Weight

388.82

Formula

C16H15ClF2N2O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=C(F)C=CC=C1F)CN(C2=CC(Cl)=CC=C2C)S(=O)(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (642.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5719 mL 12.8594 mL 25.7188 mL
5 mM 0.5144 mL 2.5719 mL 5.1438 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.72%

COA (255 KB) HNMR (120 KB) RP-HPLC (245 KB) LCMS (383 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5719 mL 12.8594 mL 25.7188 mL 64.2971 mL
5 mM 0.5144 mL 2.5719 mL 5.1438 mL 12.8594 mL
10 mM 0.2572 mL 1.2859 mL 2.5719 mL 6.4297 mL
15 mM 0.1715 mL 0.8573 mL 1.7146 mL 4.2865 mL
20 mM 0.1286 mL 0.6430 mL 1.2859 mL 3.2149 mL
25 mM 0.1029 mL 0.5144 mL 1.0288 mL 2.5719 mL
30 mM 0.0857 mL 0.4286 mL 0.8573 mL 2.1432 mL
40 mM 0.0643 mL 0.3215 mL 0.6430 mL 1.6074 mL
50 mM 0.0514 mL 0.2572 mL 0.5144 mL 1.2859 mL
60 mM 0.0429 mL 0.2143 mL 0.4286 mL 1.0716 mL
80 mM 0.0321 mL 0.1607 mL 0.3215 mL 0.8037 mL
100 mM 0.0257 mL 0.1286 mL 0.2572 mL 0.6430 mL
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FPH1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FPH1708219-39-0BRD6125FPH 1FPH-1BRD 6125BRD-6125OthersInhibitorinhibitorinhibit

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