TOMM6 - translocase of outer mitochondrial membrane 6 Gene

Homo sapiens

Also known as OBTP; TOM6

Gene ID: 100188893 | Gene type: protein coding

About TOMM6

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:41,787,694-41,789,895 (from NCBI)

This gene has 2 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in adrenal (RPKM 63.4), kidney (RPKM 57.9) and 25 other tissues.

Summary

Predicted to be involved in protein transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

TOMM6 Products(2)

mRNA	Protein	Name
NM_001134493.2	NP_001127965.1	mitochondrial import receptor subunit TOM6 homolog
NM_001382294.1	NP_001369223.1	mitochondrial import receptor subunit TOM6 homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TOMM6 Protein Structure

TOM6p

0
74 a.a.

Protein Preferred Names

Protein Names

mitochondrial import receptor subunit TOM6 homolog

over-expressed breast tumor protein

TOMM6 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TOMM6	Q96B49	ODF4	Homo sapiens	Q2M2E3	Y2H Array	32296183
Intra	TOMM6	Q96B49	ODF4	Homo sapiens	Q2M2E3	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	TOMM6	Q96B49	C1orf159	Homo sapiens	Q96HA4-2	Y2H Array	32296183
Intra	TOMM6	Q96B49	C1orf159	Homo sapiens	Q96HA4-2	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	C1orf159	Homo sapiens	Q96HA4-2	Validated Y2H	32296183
Intra	TOMM6	Q96B49	FFAR3	Homo sapiens	O14843	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	FFAR3	Homo sapiens	O14843	Y2H Array	32296183
Intra	TOMM6	Q96B49	SLC18A2	Homo sapiens	Q05940	Y2H Array	32296183
Intra	TOMM6	Q96B49	SLC18A2	Homo sapiens	Q05940	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	CERS4	Homo sapiens	Q9HA82	Validated Y2H	32296183
Intra	TOMM6	Q96B49	CERS4	Homo sapiens	Q9HA82	Y2H Array	32296183
Intra	TOMM6	Q96B49	CERS4	Homo sapiens	Q9HA82	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	CD68	Homo sapiens	P34810	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	CD68	Homo sapiens	P34810	Y2H Array	32296183
Intra	TOMM6	Q96B49	SLC10A1	Homo sapiens	Q14973	Y2H Array	32296183
Intra	TOMM6	Q96B49	SLC10A1	Homo sapiens	Q14973	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
Intra	TOMM6	Q96B49	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
Intra	TOMM6	Q96B49	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
Intra	TOMM6	Q96B49	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183
Intra	TOMM6	Q96B49	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
Intra	TOMM6	Q96B49	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14885	TOMM6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TOMM6	RGD	RGD:1583567
Canis familiaris	TOMM6	VGNC	VGNC:49103
Felis catus	TOMM6	VGNC	VGNC:102539
Mus musculus	TOMM6	MGD	MGI:1913369

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