SNAPC5 - small nuclear RNA activating complex polypeptide 5 Gene

Homo sapiens

Also known as SNAP19

Gene ID: 10302 | Gene type: protein coding

About SNAPC5

Cytogenetic location: 15q22.31 Genomic coordinates (GRCh38): 15:66,489,748-66,497,762 (from NCBI)

This gene has 8 transcripts (splice variants) and 183 orthologues. Ubiquitous expression in brain (RPKM 30.5), fat (RPKM 21.0) and 25 other tissues.

Summary

This gene encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes. This complex binds to the promoters of snRNA genes transcribed by either RNA polymerase II or III and recruits other regulatory factors to activate snRNA gene transcription. The encoded protein may play a role in stabilizing this complex. A pseudogene of this gene has been identified on chromosome 6. [provided by RefSeq, Jul 2016]

SNAPC5 Products(4)

mRNA	Protein	Name
NM_001329613.2	NP_001316542.1	snRNA-activating protein complex subunit 5 isoform 2
NM_001329614.2	NP_001316543.1	snRNA-activating protein complex subunit 5 isoform 3
NM_001329615.2	NP_001316544.1	snRNA-activating protein complex subunit 5 isoform 1
NM_006049.4	NP_006040.1	snRNA-activating protein complex subunit 5 isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA polymerase II general transcription initiation factor activity	IDA IDA: Inferred from direct assay	9732265	GOA
enables RNA polymerase III general transcription initiation factor activity	IDA IDA: Inferred from direct assay	9732265	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	11056176	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in snRNA transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	9732265	GOA
involved in snRNA transcription by RNA polymerase III	IDA IDA: Inferred from direct assay	9732265	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNAPC5 Protein Structure

SNAPc19

0
98 a.a.

Protein Preferred Names

Protein Names

snRNA-activating protein complex subunit 5

SNAPc 19 kDa subunit

Related Diseases

Diseases

Alias

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13480	SNAPC5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SNAPC5	VGNC	VGNC:35057
Rattus norvegicus	SNAPC5	RGD	RGD:1582813
Felis catus	SNAPC5	VGNC	VGNC:65523
Macaca mulatta	SNAPC5	VGNC	VGNC:77712
Mus musculus	SNAPC5	MGD	MGI:1914282
Canis familiaris	SNAPC5	VGNC	VGNC:46594

Name
Email *

	Sorry, but the email address you supplied was invalid.