2. Gene
  3. NMI - N-myc and STAT interactor Gene

NMI - N-myc and STAT interactor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 9111 | Gene type: protein coding

About NMI

Cytogenetic location: 2q23.3 Genomic coordinates (GRCh38): 2:151,270,470-151,289,668 (from NCBI)

This gene has 4 transcripts (splice variants), 195 orthologues and 2 paralogues. Ubiquitous expression in appendix (RPKM 16.7), bone marrow (RPKM 15.4) and 24 other tissues.

Summary

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in Cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]

NMI Products(1)

mRNA Protein Name
NM_004688.3 NP_004679.2 N-myc-interactor

NMI Protein Structure

IFP_35_N

IFP_35_N: Interferon-induced 35 kDa protein (IFP 35) N-terminus (29 - 104)

NID

NID: Nmi/IFP 35 domain (NID) (105 - 192)

NID

NID: Nmi/IFP 35 domain (NID) (203 - 291)

  • 0
  • 100
  • 200
  • 307 a.a.
Protein Preferred Names Protein Names

N-myc-interactor

Related Diseases

Diseases Alias
Mouth Disease

Mouth Diseases

Mouth Disorders
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101540 NMI 8739 Agonist 99.02% Unkown
HY-RS09381 NMI Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NMI VGNC VGNC:75359
Mus musculus NMI MGD MGI:1928368
Felis catus NMI VGNC VGNC:68505
Canis familiaris NMI VGNC VGNC:43861
Rattus norvegicus NMI RGD RGD:1311721
Bos taurus NMI VGNC VGNC:56132