2. Gene
  3. EMC8 - ER membrane protein complex subunit 8 Gene

EMC8 - ER membrane protein complex subunit 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NOC4; COX4NB; C16orf2; C16orf4; FAM158B

Gene ID: 10328 | Gene type: protein coding

About EMC8

Cytogenetic location: 16q24.1 Genomic coordinates (GRCh38): 16:85,778,624-85,799,544 (from NCBI)

This gene has 6 transcripts (splice variants), 208 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 7.1), testis (RPKM 6.1) and 25 other tissues.

Summary

Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in cytosol. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022]

EMC8 Products(2)

mRNA Protein Name
NM_001142288.2 NP_001135760.1 ER membrane protein complex subunit 8 isoform 2
NM_006067.5 NP_006058.1 ER membrane protein complex subunit 8 isoform 1

EMC8 Protein Structure

UPF0172

UPF0172: Uncharacterised protein family (UPF0172) (1 - 204)

  • 0
  • 100
  • 210 a.a.
Protein Preferred Names Protein Names

ER membrane protein complex subunit 8

COX4 neighbor

Recombinant EMC8 Proteins

Cat. No. Product Name Accession Purity
HY-P77342 COX4NB Protein, Human (His) O43402-1 (M1-C210) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04342 EMC8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta EMC8 VGNC VGNC:72259
Canis familiaris EMC8 VGNC VGNC:40337
Rattus norvegicus EMC8 RGD RGD:1311219
Bos taurus EMC8 VGNC VGNC:28467
Mus musculus EMC8 MGD MGI:1343095