2. Gene
  3. ARID3B - AT-rich interaction domain 3B Gene

ARID3B - AT-rich interaction domain 3B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BDP; DRIL2

Gene ID: 10620 | Gene type: protein coding

About ARID3B

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,541,220-74,598,131 (from NCBI)

This gene has 6 transcripts (splice variants), 270 orthologues and 2 paralogues. Broad expression in testis (RPKM 16.7), placenta (RPKM 10.6) and 19 other tissues.

Summary

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

ARID3B Products(2)

mRNA Protein Name
NM_001307939.2 NP_001294868.1 AT-rich interactive domain-containing protein 3B isoform 1
NM_006465.4 NP_006456.1 AT-rich interactive domain-containing protein 3B isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21044950 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARID3B Protein Structure

ARID

ARID: ARID/BRIGHT DNA binding domain (215 - 303)

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  • 500
  • 560 a.a.
Protein Preferred Names Protein Names

AT-rich interactive domain-containing protein 3B

ARID domain-containing protein 3B

Related Diseases

Diseases Alias
Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00970 ARID3B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ARID3B VGNC VGNC:38096
Rattus norvegicus ARID3B RGD RGD:1306335
Macaca mulatta ARID3B VGNC VGNC:69827
Felis catus ARID3B VGNC VGNC:59915
Mus musculus ARID3B MGD MGI:1930768
Bos taurus ARID3B VGNC VGNC:26127