2. Gene
  3. ECD - ecdysoneless cell cycle regulator Gene

ECD - ecdysoneless cell cycle regulator Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GCR2; SGT1; HSGT1

Gene ID: 11319 | Gene type: protein coding

About ECD

Cytogenetic location: 10q22.2 Genomic coordinates (GRCh38): 10:73,133,668-73,168,095 (from NCBI)

This gene has 8 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in testis (RPKM 14.0), thyroid (RPKM 12.4) and 25 other tissues.

Summary

Enables Histone Acetyltransferase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ECD Products(3)

mRNA Protein Name
NM_001135752.1 NP_001129224.1 protein ecdysoneless homolog isoform 2
NM_001135753.1 NP_001129225.1 protein ecdysoneless homolog isoform 3
NM_007265.3 NP_009196.1 protein ecdysoneless homolog isoform 1

ECD Protein Structure

SGT1

SGT1: SGT1 protein (13 - 597)

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  • 644 a.a.
Protein Preferred Names Protein Names

protein ecdysoneless homolog

ecdysoneless homolog

Recombinant ECD Proteins

Cat. No. Product Name Accession Purity
HY-P74182 ECD Protein, Human (sf9, His-GST) O95905-1 (M1-N644) ≥95%

Related Diseases

Diseases Alias
Cerebral Primitive Neuroectodermal Tumor

Pnet Of Cerebrum
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99380 Zanidatamab Inhibitor 95.06% Phase 3
Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18377 Bioymifi ≥98.0% Unkown
HY-RS04132 ECD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99963 Sudubrilimab Inhibitor / Unkown
HY-P990759 Rezetamig / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ECD VGNC VGNC:71852
Rattus norvegicus ECD RGD RGD:1565023
Canis familiaris ECD VGNC VGNC:40180
Felis catus ECD VGNC VGNC:61706
Bos taurus ECD VGNC VGNC:28301
Mus musculus ECD MGD MGI:1917851
Macaca fascicularis ECD NCBI NCBI:102129143
Others ECD NCBI