2. Gene
  3. Afp - alpha fetoprotein Gene

Afp - alpha fetoprotein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 11576 | Gene type: protein coding

About Afp

Summary

Predicted to enable fatty acid binding activity and zinc ion binding activity. Acts upstream of or within SMAD protein signal transduction; ovulation from ovarian follicle; and progesterone metabolic process. Located in cytoplasm and extracellular space. Is expressed in several structures, including amniotic fluid; egg cylinder; gut; liver and biliary system; and metanephros. Human ortholog(s) of this gene implicated in hepatitis C. Orthologous to human AFP (alpha fetoprotein). [provided by Alliance of Genome Resources, Apr 2022]

Afp Products(1)

mRNA Protein Name
NM_007423.4 NP_031449.3 alpha-fetoprotein precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within apoptotic process IMP
IMP: Inferred from mutant phenotype
36301669 MGI
acts upstream of or within homeostasis of number of cells IMP
IMP: Inferred from mutant phenotype
36301669 MGI
acts upstream of or within immune response IMP
IMP: Inferred from mutant phenotype
36301669 MGI
acts upstream of or within ovulation from ovarian follicle IMP
IMP: Inferred from mutant phenotype
12297623 MGI
acts upstream of or within progesterone metabolic process IMP
IMP: Inferred from mutant phenotype
12297623 MGI
acts upstream of or within sexual reproduction IMP
IMP: Inferred from mutant phenotype
12297623 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
8607965 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
67170 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-fetoprotein

alpha-1-fetoprotein

alpha-fetoglobulin

alpha-foetoprotein

Recombinant Afp Proteins

Cat. No. Product Name Accession Purity
HY-P7464 Alpha-Fetoprotein Protein, Mouse (HEK293, His) P02772 (K19-V605) ≥95%

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0600 Tafluprost Control 99.47% Yes
HY-B0601 Tafluprost acid 99.80% Unkown
HY-116733 Tafluprost ethyl ester Agonist / Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16031 AFP464 free base Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103469 Peroxy Orange 1 99.20% Unkown
HY-16031B AFP464 dihydrochloride Inhibitor 99.67% Unkown
HY-129293 AFP-07 free acid Agonist / Unkown
HY-160042 AFP aptamer sodium / Unkown
HY-RS00435 AFP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-105315 AFP-07 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Afp NCBI NCBI:174
Canis familiaris Afp NCBI NCBI:403551
Macaca fascicularis Afp NCBI NCBI:102130105