2. Gene
  3. ABHD15 - abhydrolase domain containing 15 Gene

ABHD15 - abhydrolase domain containing 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 116236 | Gene type: protein coding

About ABHD15

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:29,560,547-29,567,037 (from NCBI)

This gene has 1 transcript (splice variant), 167 orthologues and 3 paralogues. Ubiquitous expression in fat (RPKM 15.3), liver (RPKM 7.9) and 25 other tissues.

Summary

Predicted to enable acylglycerol Lipase activity and short-chain Carboxylesterase activity. Predicted to be involved in cellular lipid metabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

ABHD15 Products(1)

mRNA Protein Name
NM_198147.3 NP_937790.2 protein ABHD15 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ABHD15 Protein Structure

Abhydrolase_6

Abhydrolase_6: Alpha/beta hydrolase family (181 - 397)

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  • 400
  • 468 a.a.
Protein Preferred Names Protein Names

protein ABHD15

abhydrolase domain-containing protein 15

ABHD15 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ABHD15 Q6UXT9 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
ABHD15 Q6UXT9 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
ABHD15 Q6UXT9 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
ABHD15 Q6UXT9 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
ABHD15 Q6UXT9 VWC2 Homo sapiens Q2TAL6
Y2H Prey Pooling
32296183
Intra
ABHD15 Q6UXT9 VWC2 Homo sapiens Q2TAL6
Y2H Array
32296183
Intra
ABHD15 Q6UXT9 SAT1 Homo sapiens P21673
Y2H Array
32296183
Intra
ABHD15 Q6UXT9 SAT1 Homo sapiens P21673
Y2H Prey Pooling
32296183
Intra
ABHD15 Q6UXT9 WTAP Homo sapiens Q15007
Y2H Prey Pooling
32296183
Intra
ABHD15 Q6UXT9 WTAP Homo sapiens Q15007
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00089 ABHD15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ABHD15 VGNC VGNC:69539
Mus musculus ABHD15 MGD MGI:1914727
Bos taurus ABHD15 VGNC VGNC:25494
Rattus norvegicus ABHD15 RGD RGD:1304598
Felis catus ABHD15 VGNC VGNC:59480
Canis familiaris ABHD15 VGNC VGNC:37463