MRGPRX4 - MAS related GPR family member X4 Gene

Homo sapiens

Also known as GPCR; MRGX4; SNSR6

Gene ID: 117196 | Gene type: protein coding

About MRGPRX4

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:18,172,837-18,174,280 (from NCBI)

This gene has 1 transcript (splice variant), 444 orthologues and 10 paralogues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

MRGPRX4 Products(1)

mRNA	Protein	Name
NM_054032.3	NP_473373.2	mas-related G-protein coupled receptor member X4

MRGPRX4 Protein Structure

7tm_1

0
100
200
300
322 a.a.

Protein Preferred Names

Protein Names

mas-related G-protein coupled receptor member X4

G protein-coupled receptor MRGX4

Related Diseases

Diseases

Alias

Congenital Disorder Of Glycosylation, Type Ip

CDG1P	Congenital Disorder Of Glycosylation Ip
Congenital Disorder Of Glycosylation 1p	Alg11-Cdg
Cdg-Ip	Congenital Disorder Of Glycosylation Type Ip
Cdg Syndrome Type Ip	Carbohydrate Deficient Glycoprotein Syndrome Type Ip
Congenital Disorder Of Glycosylation Type 1p	Cdgip
Cdg Ip	Glycosylation, Congenital Disorder Of, Type Ip

Intrahepatic Cholestasis Of Pregnancy

Recurrent Intrahepatic Cholestasis Of Pregnancy	Gravidic Intrahepatic Cholestasis
Pregnancy-Related Cholestasis	Icp
Pregnancy Related Cholestasis	Cholestasis, Intrahepatic Of Pregnancy
Familial Intrahepatic Cholestasis Of Pregnancy	Familial Recurrent Intrahepatic Cholestasis Of Pregnancy
Ricp	Obstetric Cholestasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-148244	MS47134		99.88%	Unkown
HY-147051	MRGPRX4 modulator-2		99.64%	Unkown
HY-145997	MRGPRX4 modulator-1		99.09%	Unkown
HY-RS08652	MRGPRX4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MRGPRX4	RGD	RGD:632284

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