WIPF1 - Wipf1 WAS/WASL interacting protein family, member 1 Gene

Rattus norvegicus

Also known as Wip; Waspip

Gene ID: 117538 | Gene type: protein coding

About WIPF1

Summary

Predicted to enable SH3 domain binding activity. Involved in actin Cytoskeleton organization and positive regulation of protein export from nucleus. Located in actin filament. Orthologous to human WIPF1 (WAS/WASL interacting protein family member 1). [provided by Alliance of Genome Resources, Apr 2022]

WIPF1 Products(1)

mRNA	Protein	Name
NM_057192.2	NP_476540.2	WAS/WASL-interacting protein family member 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11687573	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	11687573	RGD
involved in positive regulation of protein export from nucleus	IDA IDA: Inferred from direct assay	11687573	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in actin filament	IDA IDA: Inferred from direct assay	11687573	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

WAS/WASL-interacting protein family member 1

WASP-interacting protein	Wiskott-Aldrich syndrome protein interacting protein
translation initiation factor IF-2-like	wiskott-Aldrich syndrome protein-interacting protein

WIPF1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Wipf1	Q6IN36	Dlg4	Rattus norvegicus	P31016	Anti Bait CoIP	16990791
Intra	Wipf1	Q6IN36	Dlg4	Rattus norvegicus	P31016	Imaging	16990791
Intra	Wipf1	Q6IN36	Wasl	Rattus norvegicus	O08816	Anti Bait CoIP	16990791
Intra	Wipf1	Q6IN36	Dnm1	Rattus norvegicus	P21575	Anti Bait CoIP	16990791

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15817	WIPF1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	WIPF1	NCBI	NCBI:7456

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