2. Gene
  3. Fabp4 - fatty acid binding protein 4, adipocyte Gene

Fabp4 - fatty acid binding protein 4, adipocyte Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ap2; P15; ALBP; Lbpl; AFABP; 422/aP2; ALBP/Ap2

Gene ID: 11770 | Gene type: protein coding

About Fabp4

Summary

Enables hormone receptor binding activity; long-chain fatty acid binding activity; and long-chain fatty acid transporter activity. Involved in long-chain fatty acid transport and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including brown fat cell differentiation; cellular response to lithium ion; and negative regulation of nitrogen compound metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including adipose tissue; central nervous system; genitourinary system; gut; and heart. Orthologous to human FABP4 (fatty acid binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Fabp4 Products(3)

mRNA Protein Name
NM_001409513.1 NP_001396442.1 fatty acid-binding protein, adipocyte isoform 2
NM_001409514.1 NP_001396443.1 fatty acid-binding protein, adipocyte isoform 3
NM_024406.4 NP_077717.1 fatty acid-binding protein, adipocyte isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables hormone receptor binding IPI
IPI: Inferred from physical interaction
12077340 MGI
enables long-chain fatty acid binding IDA
IDA: Inferred from direct assay
12077340 MGI
enables long-chain fatty acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
12077340 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within brown fat cell differentiation IDA
IDA: Inferred from direct assay
18492766 MGI
acts upstream of or within cellular response to lithium ion IDA
IDA: Inferred from direct assay
15673614 MGI
acts upstream of or within cellular response to tumor necrosis factor IDA
IDA: Inferred from direct assay
1618860 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
15684432 MGI
acts upstream of or within cytokine production IMP
IMP: Inferred from mutant phenotype
15684432 MGI
involved in long-chain fatty acid transport IDA
IDA: Inferred from direct assay
12077340 MGI
acts upstream of or within negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
15684432 MGI
acts upstream of or within negative regulation of protein kinase activity IMP
IMP: Inferred from mutant phenotype
15684432 MGI
involved in positive regulation of cold-induced thermogenesis IGI
IGI: Inferred from genetic interaction
24603714 MGI
acts upstream of or within positive regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
15684432 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
acts upstream of or within white fat cell differentiation IDA
IDA: Inferred from direct assay
18492766 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17516629 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17516629 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fatty acid-binding protein, adipocyte

3T3-L1 lipid-binding protein

P2 adipocyte protein

adipocyte lipid-binding protein

adipocyte protein aP2

adipocyte-type fatty acid-binding protein

fatty acid-binding protein 4

myelin P2 protein homolog

protein 422

Recombinant Fabp4 Proteins

Cat. No. Product Name Accession Purity
HY-P75215 FABP4 Protein, Mouse (His) NP_077717.1 (C2-A132) ≥95%
HY-P75217 FABP4 Protein, Mouse (HEK293, His) Q542H7 (M1-A132) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101903 BMS-309403 Inhibitor 99.93% Unkown
HY-101903A BMS-309403 sodium Inhibitor 99.94% Unkown
HY-148665 FABP-IN-2 Inhibitor 99.78% Unkown
HY-149953 FABP4-IN-2 Inhibitor / Unkown
HY-161702 RO6806051 Inhibitor 99.84% Unkown
HY-161892 FABP4-IN-4 Inhibitor / Unkown
HY-RS04660 FABP4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-160456 FABP4/5-IN-4 Inhibitor / Unkown
HY-160457 FABP4/5-IN-5 Inhibitor / Unkown
HY-163032 FABP4-IN-3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fabp4 NCBI NCBI:2167