1. Gene
  2. PRAP1 - proline rich acidic protein 1 Gene

PRAP1 - proline rich acidic protein 1 Gene

Homo sapiens

Also known as UPA; PRO1195

Gene ID: 118471 | Gene type: protein coding

About PRAP1

Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:133,347,373-133,352,683 (from NCBI)

This gene has 2 transcripts (splice variants) and 70 orthologues. Biased expression in small intestine (RPKM 388.5), duodenum (RPKM 348.9) and 3 other tissues.

Summary

Predicted to enable triglyceride binding activity. Involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; deactivation of mitotic spindle assembly checkpoint; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PRAP1 Products(2)

mRNA Protein Name
NM_001145201.2 NP_001138673.1 proline-rich acidic protein 1 isoform 2 precursor
NM_145202.5 NP_660203.3 proline-rich acidic protein 1 isoform 1 precursor

PRAP1 Protein Structure

PRAP

PRAP: Proline-rich acidic protein 1, pregnancy-specific uterine (105 - 149)

  • 0
  • 100
  • 151 a.a.
Protein Preferred Names Protein Names

proline-rich acidic protein 1

epididymis secretory sperm binding protein

Recombinant PRAP1 Proteins

Cat. No. Product Name Accession Purity
HY-P71004 PRAP1 Protein, Human (HEK293, His) Q96NZ9/AAL16670.1 (V21-Q151) ≥95%

Related Diseases

Diseases Alias
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PRAP1 RGD RGD:61876
Canis familiaris PRAP1 VGNC VGNC:53010
Mus musculus PRAP1 MGD MGI:893573
Bos taurus PRAP1 VGNC VGNC:55965