Cacybp - calcyclin binding protein Gene

Mus musculus

Also known as SIP

Gene ID: 12301 | Gene type: protein coding

About Cacybp

Summary

Enables protein domain specific binding activity and ubiquitin protein Ligase binding activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in cytoplasm and nuclear envelope lumen. Part of SCF ubiquitin Ligase complex. Is expressed in several structures, including alimentary system; genitourinary system; liver lobe; nervous system; and sensory organ. Orthologous to human CACYBP (calcyclin binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Cacybp Products(1)

mRNA	Protein	Name
NM_009786.2	NP_033916.1	calcyclin-binding protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables molecular adaptor activity	EXP EXP: Inferred from Experiment	15996101	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	9572262	MGI
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	15996101	MGI
enables ubiquitin protein ligase binding	EXP EXP: Inferred from Experiment	15996101	MGI
enables ubiquitin protein ligase binding	IPI IPI: Inferred from physical interaction	15996101	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to leukemia inhibitory factor	IEP IEP: Inferred from expression pattern	20439489	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of SCF ubiquitin ligase complex	IMP IMP: Inferred from mutant phenotype	15996101	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	11927578	MGI
located in nuclear envelope lumen	IDA IDA: Inferred from direct assay	11927578	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

calcyclin-binding protein

siah-interacting protein

Cacybp Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Cacybp	Q9CXW3	S100a6	Mus musculus	P14069	Affinity Chrom	12042313
Cross	Cacybp	Q9CXW3	S100P	Homo sapiens	P25815	Far-WB	12042313
Cross	Cacybp	Q9CXW3	S100B	Bos taurus	P02638	Fluorescence Spectr	12042313
Cross	Cacybp	Q9CXW3	S100A1	Bos taurus	P02639	Fluorescence Spectr	12042313
Cross	Cacybp	Q9CXW3	S100A1	Bos taurus	P02639	Affinity Chrom	12042313

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01817	CACYBP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cacybp	NCBI	NCBI:27101

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