TRAPPC5 - trafficking protein particle complex subunit 5 Gene

Homo sapiens

Also known as TRS31

Gene ID: 126003 | Gene type: protein coding

About TRAPPC5

This gene has 4 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in testis (RPKM 17.0), kidney (RPKM 16.1) and 25 other tissues.

Summary

Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Part of TRAPP complex. [provided by Alliance of Genome Resources, Apr 2022]

TRAPPC5 Products(3)

mRNA	Protein	Name
NM_001042461.3	NP_001035926.1	trafficking protein particle complex subunit 5
NM_001042462.2	NP_001035927.1	trafficking protein particle complex subunit 5
NM_174894.3	NP_777554.1	trafficking protein particle complex subunit 5

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of TRAPP complex	IDA IDA: Inferred from direct assay	21525244	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRAPPC5 Protein Structure

TRAPP

0
100
188 a.a.

Protein Preferred Names

Protein Names

trafficking protein particle complex subunit 5

trafficking protein particle complex 5

TRAPPC5 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TRAPPC5	Q8IUR0	TRAPPC2	Homo sapiens	P0DI81-3	Y2H Array	32296183
Intra	TRAPPC5	Q8IUR0	TRAPPC2	Homo sapiens	P0DI81-3	Y2H Prey Pooling	32296183
Intra	TRAPPC5	Q8IUR0	HMG20A	Homo sapiens	Q9NP66	Y2H Prey Pooling	32296183
Intra	TRAPPC5	Q8IUR0	HMG20A	Homo sapiens	Q9NP66	Y2H Array	32296183
Intra	TRAPPC5	Q8IUR0	HMG20A	Homo sapiens	Q9NP66	Validated Y2H	32296183
Intra	TRAPPC5	Q8IUR0	TRAPPC3	Homo sapiens	O43617	Y2H Prey Pooling	32296183
Intra	TRAPPC5	Q8IUR0	TRAPPC3	Homo sapiens	O43617	Anti Tag CoIP	33961781
Intra	TRAPPC5	Q8IUR0	TRAPPC3	Homo sapiens	O43617	Anti Tag CoIP	28514442
Intra	TRAPPC5	Q8IUR0	TRAPPC3	Homo sapiens	O43617	Y2H Array	32296183
Intra	TRAPPC5	Q8IUR0	CCNDBP1	Homo sapiens	O95273	Y2H Array	31515488
Intra	TRAPPC5	Q8IUR0	CCNDBP1	Homo sapiens	O95273	Validated Y2H	25416956
Intra	TRAPPC5	Q8IUR0	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	32296183
Intra	TRAPPC5	Q8IUR0	CCNDBP1	Homo sapiens	O95273	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Spondyloepiphyseal Dysplasia Tarda, X-Linked

Spondyloepiphyseal Dysplasia Tarda	X-Linked Spondyloepiphyseal Dysplasia Tarda
SEDT	Sed Tarda, X-Linked
Spondyloepiphyseal Dysplasia, Late	Spondyloepiphyseal Dysplasia Tarda X-Linked
Sed	X Linked Spondyloepiphyseal Dysplasia Tarda
X-Linked Spondyloepiphyseal Dysplasia	Late Onset Spondyloepiphyseal Dysplasia
Sed Tarda	X-Linked Sed
X-Linked Sedt	Dysplasia, Spondyloepiphyseal, Tarda
Spondyloepiphyseal Dysplasia

Binocular Vision Disease

Simultaneous Visual Perception Without Fusion

Osteogenesis Imperfecta, Type Xv

Osteogenesis Imperfecta Type 15	OI15
Osteogenesis Imperfecta Type Xv	Oi, Type Xv
Osteogenesis Imperfecta 15	Oi Type Xv
Oi-Xv

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14992	TRAPPC5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TRAPPC5	MGD	MGI:1913932
Canis familiaris	TRAPPC5	VGNC	VGNC:47784
Bos taurus	TRAPPC5	VGNC	VGNC:36291
Rattus norvegicus	TRAPPC5	RGD	RGD:1563971

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