2. Gene
  3. HMG20A - high mobility group 20A Gene

HMG20A - high mobility group 20A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HMGX1; HMGXB1

Gene ID: 10363 | Gene type: protein coding

About HMG20A

Cytogenetic location: 15q24.3 Genomic coordinates (GRCh38): 15:77,420,888-77,520,050 (from NCBI)

This gene has 12 transcripts (splice variants), 206 orthologues and 20 paralogues. Ubiquitous expression in spleen (RPKM 13.0), testis (RPKM 10.4) and 25 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of neuron differentiation; negative regulation of protein sumoylation; and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

HMG20A Products(3)

mRNA Protein Name
NM_001304504.2 NP_001291433.1 high mobility group protein 20A isoform a
NM_001304505.2 NP_001291434.1 high mobility group protein 20A isoform b
NM_018200.4 NP_060670.1 high mobility group protein 20A isoform a
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HMG20A Protein Structure

HMG_box

HMG_box: HMG (high mobility group) box (103 - 170)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
Protein Preferred Names Protein Names

high mobility group protein 20A

HMG box domain containing 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06228 HMG20A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HMG20A RGD RGD:1564760
Mus musculus HMG20A MGD MGI:1914117
Bos taurus HMG20A VGNC VGNC:29873
Macaca mulatta HMG20A VGNC VGNC:73481
Canis familiaris HMG20A VGNC VGNC:41707
Felis catus HMG20A VGNC VGNC:67592