2. Gene
  3. ARL8A - ADP ribosylation factor like GTPase 8A Gene

ARL8A - ADP ribosylation factor like GTPase 8A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GIE2; ARL10B

Gene ID: 127829 | Gene type: protein coding

About ARL8A

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:202,133,404-202,144,737 (from NCBI)

This gene has 4 transcripts (splice variants), 206 orthologues and 30 paralogues. Ubiquitous expression in brain (RPKM 56.4), bone marrow (RPKM 24.8) and 25 other tissues.

Summary

Enables GTP binding activity. Predicted to be involved in chromosome segregation. Located in cytoplasm; midbody; and spindle midzone. [provided by Alliance of Genome Resources, Apr 2022]

ARL8A Products(2)

mRNA Protein Name
NM_001256129.2 NP_001243058.1 ADP-ribosylation factor-like protein 8A isoform 2
NM_138795.4 NP_620150.1 ADP-ribosylation factor-like protein 8A isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTP binding IDA
IDA: Inferred from direct assay
15331635 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
24955142 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15331635 GOA
located in midbody IDA
IDA: Inferred from direct assay
15331635 GOA
located in spindle midzone IDA
IDA: Inferred from direct assay
15331635 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARL8A Protein Structure

Arf

Arf: ADP-ribosylation factor family (12 - 179)

  • 0
  • 100
  • 186 a.a.
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 8A

ADP-ribosylation factor-like 10B

Related Diseases

Diseases Alias
Non-Proliferative Fibrocystic Change Of The Breast

Non-Proliferative Fibrocystic Change

Breast Fibrocystic Change, Non-Proliferative Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00998 ARL8A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ARL8A RGD RGD:1565940
Felis catus ARL8A VGNC VGNC:59929
Macaca mulatta ARL8A VGNC VGNC:69900
Bos taurus ARL8A VGNC VGNC:26153
Mus musculus ARL8A MGD MGI:1915974