TSACC - TSSK6 activating cochaperone Gene

Homo sapiens

Also known as SIP; SSTK-IP; C1orf182

Gene ID: 128229 | Gene type: protein coding

About TSACC

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,337,314-156,346,995 (from NCBI)

This gene has 8 transcripts (splice variants) and 87 orthologues. Restricted expression toward testis (RPKM 148.3).

Summary

Enables chaperone binding activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TSACC Products(11)

mRNA	Protein	Name
NM_001304817.2	NP_001291746.1	TSSK6-activating co-chaperone protein isoform a
NM_001304818.2	NP_001291747.1	TSSK6-activating co-chaperone protein isoform a
NM_001304819.2	NP_001291748.1	TSSK6-activating co-chaperone protein isoform a
NM_001304820.1	NP_001291749.1	TSSK6-activating co-chaperone protein isoform a
NM_001304821.2	NP_001291750.1	TSSK6-activating co-chaperone protein isoform a
NM_001304822.2	NP_001291751.1	TSSK6-activating co-chaperone protein isoform b
NM_001304823.2	NP_001291752.1	TSSK6-activating co-chaperone protein isoform b
NM_001304824.2	NP_001291753.1	TSSK6-activating co-chaperone protein isoform b
NM_001304825.2	NP_001291754.1	TSSK6-activating co-chaperone protein isoform b
NM_001304826.2	NP_001291755.1	TSSK6-activating co-chaperone protein isoform c
NM_144627.5	NP_653228.1	TSSK6-activating co-chaperone protein isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA
enables protein-folding chaperone binding	IPI IPI: Inferred from physical interaction	20829357	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

TSSK6-activating co-chaperone protein

SSTK-interacting protein (SSTK-IP)

TSACC Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TSACC	Q96A04	LIX1	Homo sapiens	Q8N485	Y2H Prey Pooling	32296183
Intra	TSACC	Q96A04	LIX1	Homo sapiens	Q8N485	Y2H Array	32296183
Intra	TSACC	Q96A04	ATN1	Homo sapiens	Q86V38	Validated Y2H	32814053
Intra	TSACC	Q96A04	ATN1	Homo sapiens	Q86V38	Y2H Array	32814053
Intra	TSACC	Q96A04	ATN1	Homo sapiens	Q86V38	Y2H Pooling	32814053
Intra	TSACC	Q96A04	PAK1	Homo sapiens	Q13153	Validated Y2H	32814053
Intra	TSACC	Q96A04	PAK1	Homo sapiens	Q13153	Y2H Array	32814053
Intra	TSACC	Q96A04	PAK1	Homo sapiens	Q13153	Y2H Pooling	32814053
Intra	TSACC	Q96A04	NUP58	Homo sapiens	Q9BVL2	Validated Y2H	32814053
Intra	TSACC	Q96A04	NUP58	Homo sapiens	Q9BVL2	Y2H Pooling	32814053
Intra	TSACC	Q96A04	NUP58	Homo sapiens	Q9BVL2	Y2H Array	32814053
Intra	TSACC	Q96A04	FOXP2	Homo sapiens	O15409	Y2H Array	32296183
Intra	TSACC	Q96A04	FOXP2	Homo sapiens	O15409	Y2H Prey Pooling	32296183
Intra	TSACC	Q96A04	FOXP2	Homo sapiens	O15409	Y2H Prey Pooling	25416956
Intra	TSACC	Q96A04	FOXP2	Homo sapiens	O15409	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Complete Androgen Insensitivity Syndrome

Cais	Complete Androgen Resistance Syndrome
Androgen Insensitivity Syndrome Complete	Androgen Insensitivity, Complete
Androgen-Insensitivity Syndrome	Testicular Feminization

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15129	TSACC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TSACC	VGNC	VGNC:66604
Rattus norvegicus	TSACC	RGD	RGD:1304953
Macaca mulatta	TSACC	VGNC	VGNC:79861
Bos taurus	TSACC	VGNC	VGNC:36406
Mus musculus	TSACC	MGD	MGI:1924177

Name
Email *

	Sorry, but the email address you supplied was invalid.