TRIM43 - tripartite motif containing 43 Gene

Homo sapiens

Also known as TRIM43A

Gene ID: 129868 | Gene type: protein coding

About TRIM43

This gene has 1 transcript (splice variant), 93 orthologues and 80 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM43 Products(1)

mRNA	Protein	Name
NM_138800.3	NP_620155.1	tripartite motif-containing protein 43

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRIM43 Protein Structure

zf-C3HC4_4

SPRY

0
100
200
300
400
446 a.a.

Protein Preferred Names

Protein Names

tripartite motif-containing protein 43

TRIM43 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TRIM43	Q96BQ3	GRB7	Homo sapiens	Q14451-3	Y2H Array	32296183
Intra	TRIM43	Q96BQ3	GRB7	Homo sapiens	Q14451-3	Y2H Prey Pooling	32296183
Intra	TRIM43	Q96BQ3	TGFBR2	Homo sapiens	P37173	Validated Y2H	32814053
Intra	TRIM43	Q96BQ3	TGFBR2	Homo sapiens	P37173	Y2H Pooling	32814053
Intra	TRIM43	Q96BQ3	TGFBR2	Homo sapiens	P37173	Y2H Array	32814053
Intra	TRIM43	Q96BQ3	UBE2K	Homo sapiens	P61086	Validated Y2H	32814053
Intra	TRIM43	Q96BQ3	UBE2K	Homo sapiens	P61086	Y2H Array	32814053
Intra	TRIM43	Q96BQ3	UBE2K	Homo sapiens	P61086	Y2H Pooling	32814053
Intra	TRIM43	Q96BQ3	ENOX1	Homo sapiens	Q8TC92	Validated Y2H	25416956
Intra	TRIM43	Q96BQ3	ENOX1	Homo sapiens	Q8TC92	Y2H Prey Pooling	32296183
Intra	TRIM43	Q96BQ3	ENOX1	Homo sapiens	Q8TC92	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Facioscapulohumeral Muscular Dystrophy 1

Facioscapulohumeral Muscular Dystrophy	Fshd
Landouzy-Dejerine Muscular Dystrophy	Muscular Dystrophy, Facioscapulohumeral
FSHD1	Fshd1a
Muscular Dystrophy, Facioscapulohumeral, Type 1a	Facioscapulohumeral Muscular Dystrophy Type 1a
Fsh Muscular Dystrophy	Facioscapulohumeral Muscular Dystrophy 1a
Facioscapulohumeral Atrophy	Facioscapulohumeral Myopathy
Muscular Dystrophy, Facioscapulohumeral, Type 1	Facioscapulohumeral Muscular Dystrophy Type 1
Landouzy Dejerine Muscular Dystrophy	Muscular Dystrophy, Landouzy-Dejerine
Fshmd1a	Facio-Scapulo-Humeral Dystrophy
Facioscapulohumeral Type Progressive Muscular Dystrophy	Facioscapuloperoneal Muscular Dystrophy
Facioscapulohumeral Dystrophy	Fsh Dystrophy
Landouzy-Dejerine Dystrophy	Landouzy-Dejerine Myopathy
Fmd	Facioscapulohumeral Muscular Dystrophy-1a
Muscular Dystrophy Facioscapulohumeral	Dystrophy, Muscular, Facioscapulohumeral
Dystrophy, Muscular, Facioscapulohumeral, Type 1	Landouzy-Dejerine Disease
Landouzy-Déjerine Atrophy	Facioscapulohumeral Muscle Dystrophy
Fmd - [Facioscapulohumeral Muscular Dystrophy]	Fsh - [Facioscapulohumeral Muscular Dystrophy]
Fshd - [Facioscapulohumeral Muscular Dystrophy]	Landouzy-Déjerine Dystrophy Or Facioscapulohumeral Atrophy
Landouzy-Déjérine Muscular Dystrophy

Facioscapulohumeral Muscular Dystrophy 2, Digenic

Facioscapulohumeral Muscular Dystrophy 2	FSHD2
Fshd1b	Facioscapulohumeral Muscular Dystrophy 1b
Fshd2, Digenic	Muscular Dystrophy, Facioscapulohumeral, Type 2
Muscular Dystrophy, Facioscapulohumeral, Type 1b	Fascioscapulohumeral Muscular Dystrophy 2, Digenic
Facioscapulohumeral Muscular Dystrophy Type 2	Digenic Facioscapulohumeral Muscular Dystrophy
Digenic Fshd2	Facioscapulohumeral Muscular Dystrophy Type 1b
Dystrophy, Muscular, Facioscapulohumeral, Type 2

Digenic Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15047	TRIM43 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TRIM43	RGD	RGD:1561074

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