Eno1 - enolase 1, alpha non-neuron Gene

Mus musculus

Also known as NNE; Eno-1; MBP-1

Gene ID: 13806 | Gene type: protein coding

About Eno1

Summary

Enables RNA binding activity and phosphopyruvate hydratase activity. Acts upstream of or within cellular response to interleukin-7; in utero embryonic development; and positive regulation of binding activity. Is extrinsic component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human ENO1 (Enolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Eno1 Products(3)

mRNA	Protein	Name
NM_001379127.1	NP_001366056.1	alpha-enolase isoform 1
NM_001379128.1	NP_001366057.1	alpha-enolase isoform 2
NM_023119.2	NP_075608.2	alpha-enolase isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA binding	IDA IDA: Inferred from direct assay	21936910	MGI
enables phosphopyruvate hydratase activity	IDA IDA: Inferred from direct assay	7323947	MGI
enables phosphopyruvate hydratase activity	IMP IMP: Inferred from mutant phenotype	30679508	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	23446454	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to acid chemical	IDA IDA: Inferred from direct assay	17690254	MGI
acts upstream of or within cellular response to interleukin-7	IDA IDA: Inferred from direct assay	29581031	MGI
involved in gluconeogenesis	IMP IMP: Inferred from mutant phenotype	30679508	MGI
involved in glycolytic process	IDA IDA: Inferred from direct assay	23446454	MGI
acts upstream of or within in utero embryonic development	IMP IMP: Inferred from mutant phenotype	9626503	MGI
acts upstream of or within positive regulation of binding	IMP IMP: Inferred from mutant phenotype	17690254	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell surface	IDA IDA: Inferred from direct assay	17690254	MGI
is active in cytosol	IDA IDA: Inferred from direct assay	23512986	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

alpha-enolase

2-phospho-D-glycerate hydro-lyase	2-phospho-D-glycerate hydrolase
c-Myc promoter binding protein	non-neural enolase

Recombinant Eno1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72182	Enolase 1/ENO1 Protein, Mouse (His)	P17182 (S2-A433)	≥95%

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108868	Mersalyl	Inducer	≥80.0%	Unkown

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-131904	POMHEX		99.54%	Unkown
HY-117778	SF2312	Inhibitor	≥95.0%	Unkown
HY-131904A	Hex	Inhibitor	99.96%	Unkown
HY-117778B	SF2312 ammonium	Inhibitor	≥98.0%	Unkown
HY-102062	Nω-Propyl-L-arginine	Inhibitor	98.62%	Unkown
HY-102062A	Nω-Propyl-L-arginine hydrochloride	Inhibitor	98.28%	Unkown
HY-W003969	Aminopicoline	Inhibitor	99.96%	Unkown
HY-162168	Anti-inflammatory agent 71	Inhibitor	/	Unkown
HY-RS04378	ENO1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Eno1	NCBI	NCBI:2023
Rattus norvegicus	Eno1	NCBI	NCBI:24333

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