2. Gene
  3. CSN3 - casein kappa Gene

CSN3 - casein kappa Gene

  • Gene
  • Protein
  • Disease
  • Agent
Homo sapiens

Also known as KCA; CSNK; CNS10; CSN10

Gene ID: 1448 | Gene type: protein coding

About CSN3

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,238,381-70,251,432 (from NCBI)

This gene has 2 transcripts (splice variants) and 84 orthologues. Restricted expression toward salivary gland (RPKM 13.6).

Summary

Involved in lactation and protein stabilization. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

CSN3 Products(2)

mRNA Protein Name
NM_001394997.1 NP_001381926.1 kappa-casein precursor
NM_005212.3 NP_005203.2 kappa-casein precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Reference Source
involved in lactation IDA
IDA: Inferred from direct assay
7979373 GOA
involved in protein stabilization IDA
IDA: Inferred from direct assay
7979373 GOA
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
7979373 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CSN3 Protein Structure

Casein_kappa

Casein_kappa: Kappa casein (21 - 181)

  • 0
  • 100
  • 182 a.a.
Protein Preferred Names Protein Names

kappa-casein

CSN3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CSN3 P07498 ZNF76 Homo sapiens P36508
Validated Y2H
32296183
Intra
CSN3 P07498 RBPMS Homo sapiens Q93062
Y2H Array
25416956
Intra
CSN3 P07498 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
32296183
Intra
CSN3 P07498 UBQLN1 Homo sapiens Q9UMX0
Validated Y2H
32296183
Intra
CSN3 P07498 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
32296183
Intra
CSN3 P07498 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
CSN3 P07498 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
CSN3 P07498 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CSN3 Proteins

Cat. No. Product Name Accession Purity
HY-P70978 Kappa-Casein Protein, Human (HEK293, His) AAH10935.1 (E21-A182) ≥95%

Related Diseases

Diseases Alias
Milk Allergy

Milk Allergic Reaction

Milk Hypersensitivity

Allergy Milk
Food Allergy

Food Hypersensitivity

Food Allergies

Allergy Food

Food Allergen-Induced Hypersensitivity
Mastitis

Breast Inflammation

Inflammatory Breast Disease

Inflammatory Disease Of Breast

Inflammation Of Non-Human Mammary Gland

Inflammatory Disorder Of Breast

Mastitis Nos

Acute Mastitis Nos

Acute Nonpuerperal Mastitis

Nonpuerperal Mastitis Nos

Subacute Mastitis Nos
Cow Milk Allergy

Bos Taurus Milk Allergy

Cow'S Milk Protein Sensitivity
Dentin Sensitivity

Sensitive Dentin
Epilepsy, Juvenile Absence 1

Epilepsy, Juvenile Absence, Susceptibility To, 1

EJA1

JAE1

Juvenile Absence Epilepsy 1

Susceptibility To Juvenile Absence Epilepsy 1

Epilepsy, Juvenile Absence, Susceptibility To, Type 1

Absence Epilepsy
Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo
Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03244 CSN3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown