PATE1 - prostate and testis expressed 1 Gene

Homo sapiens

Also known as PATE

Gene ID: 160065 | Gene type: protein coding

About PATE1

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:125,746,279-125,749,867 (from NCBI)

This gene has 3 transcripts (splice variants), 76 orthologues and 4 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable acetylcholine receptor regulator activity. Predicted to be involved in regulation of neurotransmitter receptor activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PATE1 Products(1)

mRNA	Protein	Name
NM_138294.3	NP_612151.1	prostate and testis expressed protein 1 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

prostate and testis expressed protein 1

expressed in prostate and testis

PATE1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PATE1	Q8WXA2	SERTAD1	Homo sapiens	Q53GC0	Validated Y2H	25416956
Intra	PATE1	Q8WXA2	REL	Homo sapiens	Q04864	Validated Y2H	25416956
Intra	PATE1	Q8WXA2	REL	Homo sapiens	Q04864	Y2H Array	25416956
Intra	PATE1	Q8WXA2	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	25416956
Intra	PATE1	Q8WXA2	INCA1	Homo sapiens	Q0VD86	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10079	PATE1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PATE1	MGD	MGI:4936886
Rattus norvegicus	PATE1	RGD	RGD:2319716
Macaca mulatta	PATE1	VGNC	VGNC:101374

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