2. Gene
  3. UBXN2A - UBX domain protein 2A Gene

UBXN2A - UBX domain protein 2A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as UBXD4

Gene ID: 165324 | Gene type: protein coding

About UBXN2A

This gene has 4 transcripts (splice variants), 208 orthologues and 3 paralogues. Ubiquitous expression in fat (RPKM 3.2), esophagus (RPKM 2.9) and 25 other tissues.

Summary

Predicted to enable ubiquitin binding activity. Predicted to be involved in several processes, including autophagosome assembly; nuclear membrane reassembly; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to leukemia inhibitory factor; regulation of gene expression; and regulation of protein metabolic process. Predicted to be located in cis-Golgi network and endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

UBXN2A Products(1)

mRNA Protein Name
NM_181713.4 NP_859064.2 UBX domain-containing protein 2A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21900206 GOA
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of ERAD pathway IMP
IMP: Inferred from mutant phenotype
26265139 GOA
involved in negative regulation of proteolysis IMP
IMP: Inferred from mutant phenotype
26634371 GOA
involved in positive regulation of protein catabolic process IMP
IMP: Inferred from mutant phenotype
37037900 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24625977 GOA
located in nucleus IDA
IDA: Inferred from direct assay
24625977 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UBXN2A Protein Structure

SEP

SEP: SEP domain (65 - 138)

UBX

UBX: UBX domain (172 - 246)

  • 0
  • 100
  • 200
  • 259 a.a.
Protein Preferred Names Protein Names

UBX domain-containing protein 2A

UBX domain containing 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15396 UBXN2A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta UBXN2A VGNC VGNC:79657
Canis familiaris UBXN2A VGNC VGNC:48098
Mus musculus UBXN2A MGD MGI:2442310
Felis catus UBXN2A VGNC VGNC:66792
Bos taurus UBXN2A VGNC VGNC:36625
Rattus norvegicus UBXN2A RGD RGD:1589027