2. Gene
  3. Ccl3 - chemokine (C-C motif) ligand 3 Gene

Ccl3 - chemokine (C-C motif) ligand 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mip1a; Scya3; G0S19-1; MIP1-(a); LD78alpha; MIP-1alpha; MIP1-alpha

Gene ID: 20302 | Gene type: protein coding

About Ccl3

Summary

Enables chemokine activity. Involved in several processes, including astrocyte cell migration; macrophage chemotaxis; and positive regulation of macromolecule metabolic process. Located in extracellular space. Is expressed in articular cartilage; cartilage; knee joint; lung; and radius. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL3 (C-C motif chemokine ligand 3). [provided by Alliance of Genome Resources, Apr 2022]

Ccl3 Products(1)

mRNA Protein Name
NM_011337.2 NP_035467.1 C-C motif chemokine 3 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chemokine activity IDA
IDA: Inferred from direct assay
7594543 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
7594543 MGI
Biological Process GO Annotation Evidence Reference Source
involved in astrocyte cell migration IDA
IDA: Inferred from direct assay
15155903 MGI
involved in macrophage chemotaxis IGI
IGI: Inferred from genetic interaction
21784977 MGI
involved in positive regulation of inflammatory response IGI
IGI: Inferred from genetic interaction
21784977 MGI
involved in positive regulation of interleukin-1 beta production IGI
IGI: Inferred from genetic interaction
21784977 MGI
involved in positive regulation of neuron apoptotic process IGI
IGI: Inferred from genetic interaction
15155903 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
15155903 MGI
involved in positive regulation of tumor necrosis factor production IGI
IGI: Inferred from genetic interaction
21784977 MGI
involved in regulation of cell shape IDA
IDA: Inferred from direct assay
15155903 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
19139201 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 3

L2G25B

MIP-1-alpha

MIP1 (a)

SIS-alpha

TY-5

heparin-binding chemotaxis protein

macrophage inflammatory protein 1-alpha

macrophage inflammatory protein-1alpha

small-inducible cytokine A3

Recombinant Ccl3 Proteins

Cat. No. Product Name Accession Purity
HY-P7255 MIP-1 alpha/CCL3 Protein, Mouse (HEK293) P10855 (A24-A92) ≥95%
HY-P7768 MIP-1 alpha/CCL3 Protein, Mouse (His) P10855/Q5SVU3 (A24-A92) ≥95%
HY-P7768AF Animal-Free MIP-1 alpha/CCL3 Protein, Mouse (His) P10855 (A24-A92) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B0498 Bindarit Inhibitor 99.53% Phase 3
Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149202 UT-11 Inhibitor 99.62% Unkown
HY-147660 IMMH001 Agonist 98.10% Unkown
HY-124668 CCR1 antagonist 12 Antagonist / Unkown
HY-RS02099 CCL3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02100 CCL3L1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02101 CCL3L3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W505771 Seselin Inhibitor 98.48% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl3 NCBI NCBI:6348
Rattus norvegicus Ccl3 NCBI NCBI:25542