N4BP3 - NEDD4 binding protein 3 Gene

Homo sapiens

Also known as LZTS4

Gene ID: 23138 | Gene type: protein coding

About N4BP3

Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38): 5:178,113,532-178,127,034 (from NCBI)

This gene has 1 transcript (splice variant) and 197 orthologues. Broad expression in placenta (RPKM 5.5), esophagus (RPKM 3.2) and 20 other tissues.

Summary

Predicted to be involved in nervous system development. Predicted to be located in axon and dendrite. Predicted to be active in cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

N4BP3 Products(1)

mRNA	Protein	Name
NM_015111.2	NP_055926.1	NEDD4-binding protein 3

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IDA IDA: Inferred from direct assay	34880843	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	26496610	GOA

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of positive effect innate immune response	IDA IDA: Inferred from direct assay	23951545	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

N4BP3 Protein Structure

Fez1

0
100
200
300
400
500
544 a.a.

Protein Preferred Names

Protein Names

NEDD4-binding protein 3

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 5

Epileptic Encephalopathy, Early Infantile, 5	DEE5
Eiee5	Developmental And Epileptic Encephalopathy, 5
Early Infantile Epileptic Encephalopathy 5	Encephalopathy, Epileptic, Early Infantile, Type 5

Developmental And Epileptic Encephalopathy 4

DEE4	Epileptic Encephalopathy, Early Infantile, 4
Eiee4	Early Infantile Epileptic Encephalopathy 4
Stxbp1-Related Early-Onset Encephalopathy	Early Myoclonic Encephalopathy
Developmental And Epileptic Encephalopathy, 4	Stxbp1 Disorders
Stxbp1 Encephalopathy	Developmental And Epileptic Encephalopathy, Type 4
Early-Infantile Epileptic Encephalopathy 4	Stxbp1 Encephalopathy With Epilepsy
Stxbp1 Epileptic Encephalopathy	Stxbp1-Related Developmental And Epileptic Encephalopathy
Stxbp1-Related Epileptic Encephalopathy	Eme
Neonatal Epilepsy With Suppression-Burst Pattern	Encephalopathy, Epileptic, Early Infantile, Type 4

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08983	N4BP3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	N4BP3	RGD	RGD:1308356
Macaca mulatta	N4BP3	VGNC	VGNC:75053
Bos taurus	N4BP3	VGNC	VGNC:31853
Canis familiaris	N4BP3	VGNC	VGNC:43598
Felis catus	N4BP3	VGNC	VGNC:102262
Mus musculus	N4BP3	MGD	MGI:2442218

Name
Email *

	Sorry, but the email address you supplied was invalid.