ECPAS - Ecm29 proteasome adaptor and scaffold Gene

Homo sapiens

Also known as ECM29; KIAA0368

Gene ID: 23392 | Gene type: protein coding

About ECPAS

Cytogenetic location: 9q31.3 Genomic coordinates (GRCh38): 9:111,360,685-111,484,383 (from NCBI)

This gene has 7 transcripts (splice variants), 210 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 17.3), fat (RPKM 15.6) and 25 other tissues.

Summary

Enables Proteasome binding activity. Involved in ubiquitin-dependent ERAD pathway. Located in several cellular components, including centrosome; cytoplasmic vesicle; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ECPAS Products(4)

mRNA	Protein	Name
NM_001363756.2	NP_001350685.1	proteasome adapter and scaffold protein ECM29 isoform 2
NM_001364929.1	NP_001351858.1	proteasome adapter and scaffold protein ECM29 isoform 3
NM_001364930.1	NP_001351859.1	proteasome adapter and scaffold protein ECM29 isoform 3
NM_001364931.1	NP_001351860.1	proteasome adapter and scaffold protein ECM29 isoform 4

ECPAS Protein Structure

Ecm29

Vac14_Fab1_bd

0
300
600
900
1200
1500
1839 a.a.

Protein Preferred Names

Protein Names

proteasome adapter and scaffold protein ECM29

ECM29 homolog, proteasome accessory protein

ECPAS Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ECPAS	Q5VYK3	TNFRSF10D	Homo sapiens	Q9UBN6	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	TNFRSF10D	Homo sapiens	Q9UBN6	Y2H Array	32296183
Intra	ECPAS	Q5VYK3	TNFRSF10D	Homo sapiens	Q9UBN6	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	CMTM6	Homo sapiens	Q9NX76	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	CMTM6	Homo sapiens	Q9NX76	Y2H Array	32296183
Intra	ECPAS	Q5VYK3	CMTM6	Homo sapiens	Q9NX76	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	AGTRAP	Homo sapiens	Q6RW13-2	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Array	32296183
Intra	ECPAS	Q5VYK3	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Array	32296183
Intra	ECPAS	Q5VYK3	CMTM5	Homo sapiens	Q96DZ9-2	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	DGAT2L6	Homo sapiens	Q6ZPD8	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	DGAT2L6	Homo sapiens	Q6ZPD8	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	DGAT2L6	Homo sapiens	Q6ZPD8	Y2H Array	32296183
Intra	ECPAS	Q5VYK3	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Array	32296183
Intra	ECPAS	Q5VYK3	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	HSD17B13	Homo sapiens	Q7Z5P4	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	CMTM5	Homo sapiens	Q96DZ9	Y2H Prey Pooling	25416956
Intra	ECPAS	Q5VYK3	CMTM5	Homo sapiens	Q96DZ9	Validated Y2H	25416956
Intra	ECPAS	Q5VYK3	BSND	Homo sapiens	Q8WZ55	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	BSND	Homo sapiens	Q8WZ55	Y2H Array	32296183
Intra	ECPAS	Q5VYK3	BSND	Homo sapiens	Q8WZ55	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	MAL2	Homo sapiens	Q969L2	Y2H Prey Pooling	32296183
Intra	ECPAS	Q5VYK3	MAL2	Homo sapiens	Q969L2	Validated Y2H	32296183
Intra	ECPAS	Q5VYK3	MAL2	Homo sapiens	Q969L2	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04145	ECPAS Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ECPAS	VGNC	VGNC:30551
Canis familiaris	ECPAS	VGNC	VGNC:42346
Mus musculus	ECPAS	MGD	MGI:2140220
Macaca mulatta	ECPAS	VGNC	VGNC:72137
Rattus norvegicus	ECPAS	RGD	RGD:1306148
Felis catus	ECPAS	VGNC	VGNC:61713

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