CARHSP1 - calcium regulated heat stable protein 1 Gene

Homo sapiens

Also known as CSDC1; CRHSP24; CRHSP-24

Gene ID: 23589 | Gene type: protein coding

About CARHSP1

Cytogenetic location: 16p13.2 Genomic coordinates (GRCh38): 16:8,852,942-8,869,006 (from NCBI)

This gene has 20 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 17.9), adrenal (RPKM 11.8) and 25 other tissues.

Summary

Enables mRNA 3'-UTR binding activity. Predicted to be involved in regulation of mRNA stability. Predicted to be located in P granule and cytosol. Predicted to be active in cytoplasm. Predicted to colocalize with cytoplasmic exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]

CARHSP1 Products(9)

mRNA	Protein	Name
NM_001042476.2	NP_001035941.1	calcium-regulated heat-stable protein 1
NM_001278260.2	NP_001265189.1	calcium-regulated heat-stable protein 1
NM_001278261.2	NP_001265190.1	calcium-regulated heat-stable protein 1
NM_001278262.2	NP_001265191.1	calcium-regulated heat-stable protein 1
NM_001278263.1	NP_001265192.1	calcium-regulated heat-stable protein 1
NM_001278264.2	NP_001265193.1	calcium-regulated heat-stable protein 1
NM_001278265.2	NP_001265194.1	calcium-regulated heat-stable protein 1
NM_001278266.2	NP_001265195.1	calcium-regulated heat-stable protein 1
NM_014316.4	NP_055131.2	calcium-regulated heat-stable protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables mRNA 3'-UTR binding	IDA IDA: Inferred from direct assay	21078874	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CARHSP1 Protein Structure

CSD

0
100
147 a.a.

Protein Preferred Names

Protein Names

calcium-regulated heat-stable protein 1

calcium regulated heat stable protein 1, 24kDa

CARHSP1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CARHSP1	Q9Y2V2	KRTAP10-8	Homo sapiens	P60410	Validated Y2H	25416956
Intra	CARHSP1	Q9Y2V2	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	CARHSP1	Q9Y2V2	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	CARHSP1	Q9Y2V2	KRTAP10-7	Homo sapiens	P60409	Validated Y2H	25416956
Intra	CARHSP1	Q9Y2V2	KRTAP10-7	Homo sapiens	P60409	Y2H Array	25416956
Intra	CARHSP1	Q9Y2V2	MID2	Homo sapiens	Q9UJV3-2	Y2H Array	32296183
Intra	CARHSP1	Q9Y2V2	MID2	Homo sapiens	Q9UJV3-2	Y2H Prey Pooling	32296183
Intra	CARHSP1	Q9Y2V2	DOCK8	Homo sapiens	Q8NF50-2	Validated Y2H	25416956
Intra	CARHSP1	Q9Y2V2	DOCK8	Homo sapiens	Q8NF50-2	Y2H Array	25416956
Intra	CARHSP1	Q9Y2V2	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Array	32296183
Intra	CARHSP1	Q9Y2V2	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Prey Pooling	32296183
Intra	CARHSP1	Q9Y2V2	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Array	32296183
Intra	CARHSP1	Q9Y2V2	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Prey Pooling	32296183
Intra	CARHSP1	Q9Y2V2	DOCK8	Homo sapiens	Q8NF50	Validated Y2H	25416956
Intra	CARHSP1	Q9Y2V2	PNMA1	Homo sapiens	Q8ND90	Y2H Prey Pooling	25416956
Intra	CARHSP1	Q9Y2V2	PNMA1	Homo sapiens	Q8ND90	Validated Y2H	25416956
Intra	CARHSP1	Q9Y2V2	AKAP8L	Homo sapiens	Q9ULX6	Y2H Prey Pooling	32296183
Intra	CARHSP1	Q9Y2V2	AKAP8L	Homo sapiens	Q9ULX6	Y2H Array	32296183
Intra	CARHSP1	Q9Y2V2	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	CARHSP1	Q9Y2V2	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	CARHSP1	Q9Y2V2	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	32296183
Intra	CARHSP1	Q9Y2V2	GORASP2	Homo sapiens	Q9H8Y8	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CARHSP1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76766	CARHSP1 Protein, Human (His)	Q9Y2V2 (M1-S147)	≥95%

Related Diseases

Diseases

Alias

Chromosome 8q21.11 Deletion Syndrome

8q21.11 Microdeletion Syndrome	Del(8)(Q21.11)
Deletion 8q21.11	Monosomy 8q21.11

Thrombocytopenia-Absent Radius Syndrome

Tar Syndrome	Radial Aplasia-Thrombocytopenia Syndrome
Absent Radii And Thrombocytopenia	TAR
Chromosome 1q21.1 Deletion Syndrome, 200-Kb	Thrombocytopenia Absent Radius Syndrome
Thrombocytopenia Absent Radii	Chromosome 1q21.1 Deletion Syndrome
Thrombocytopenia With Absent Radii Syndrome	Radial Aplasia-Amegakaryocytic Thrombocytopenia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01925	CARHSP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CARHSP1	VGNC	VGNC:26766
Mus musculus	CARHSP1	MGD	MGI:1196368
Canis familiaris	CARHSP1	VGNC	VGNC:38720
Rattus norvegicus	CARHSP1	RGD	RGD:708415
Macaca mulatta	CARHSP1	VGNC	VGNC:99498
Felis catus	CARHSP1	VGNC	VGNC:80555
Others	CARHSP1	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.