1. Gene
  2. GORASP2 - golgi reassembly stacking protein 2 Gene

GORASP2 - golgi reassembly stacking protein 2 Gene

Homo sapiens

Also known as p59; GRS2; GOLPH6; GRASP55

Gene ID: 26003 | Gene type: protein coding

About GORASP2

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:170,928,477-170,967,130 (from NCBI)

This gene has 11 transcripts (splice variants), 268 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 25.6), placenta (RPKM 23.9) and 25 other tissues.

Summary

This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during Apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

GORASP2 Products(2)

mRNA Protein Name
NM_001201428.2 NP_001188357.1 Golgi reassembly-stacking protein 2 isoform 2
NM_015530.5 NP_056345.3 Golgi reassembly-stacking protein 2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence Reference Source
involved in establishment of protein localization to plasma membrane IDA
IDA: Inferred from direct assay
28067262 GOA
involved in establishment of protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
21884936 GOA
involved in organelle assembly IMP
IMP: Inferred from mutant phenotype
22523075 GOA
involved in organelle organization IMP
IMP: Inferred from mutant phenotype
21515684 GOA
involved in response to endoplasmic reticulum stress IDA
IDA: Inferred from direct assay
21884936 GOA
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
28067262 GOA
located in Golgi membrane IDA
IDA: Inferred from direct assay
27062250 GOA
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
27062250 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GORASP2 Protein Structure

GRASP55_65

GRASP55_65: GRASP55/65 PDZ-like domain (69 - 204)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 452 a.a.
Protein Preferred Names Protein Names

Golgi reassembly-stacking protein 2

golgi phosphoprotein 6

GORASP2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
GORASP2 Q9H8Y8 PNMA5 Homo sapiens Q96PV4 25416956
Intra
GORASP2 Q9H8Y8 PNMA5 Homo sapiens Q96PV4 32296183
Intra
GORASP2 Q9H8Y8 PNMA5 Homo sapiens Q96PV4 25416956
Intra
GORASP2 Q9H8Y8 PNMA5 Homo sapiens Q96PV4 32296183
Intra
GORASP2 Q9H8Y8 MID2 Homo sapiens Q9UJV3-2 32296183
Intra
GORASP2 Q9H8Y8 MID2 Homo sapiens Q9UJV3-2 32296183
Intra
GORASP2 Q9H8Y8 MID2 Homo sapiens Q9UJV3-2 32296183
Intra
GORASP2 Q9H8Y8 MID2 Homo sapiens Q9UJV3-2 25416956
Intra
GORASP2 Q9H8Y8 RGS3 Homo sapiens P49796-8 25416956
Intra
GORASP2 Q9H8Y8 DRC12 Homo sapiens Q494R4 25416956
Intra
GORASP2 Q9H8Y8 DRC12 Homo sapiens Q494R4 25416956
Intra
GORASP2 Q9H8Y8 GOLGA6L2 Homo sapiens Q8N9W4-2 32296183
Intra
GORASP2 Q9H8Y8 GOLGA6L2 Homo sapiens Q8N9W4-2 32296183
Intra
GORASP2 Q9H8Y8 AAMDC Homo sapiens Q9H7C9 25416956
Intra
GORASP2 Q9H8Y8 AAMDC Homo sapiens Q9H7C9 25416956
Intra
GORASP2 Q9H8Y8 TSN Homo sapiens Q15631 32296183
Intra
GORASP2 Q9H8Y8 TSN Homo sapiens Q15631 32296183
Intra
GORASP2 Q9H8Y8 TAGLN Homo sapiens Q01995 32296183
Intra
GORASP2 Q9H8Y8 CHMP1A Homo sapiens Q9HD42 32296183
Intra
GORASP2 Q9H8Y8 DPYSL2 Homo sapiens Q16555 32296183
Intra
GORASP2 Q9H8Y8 DPYSL2 Homo sapiens Q16555 31515488
Intra
GORASP2 Q9H8Y8 DPYSL2 Homo sapiens Q16555 25416956
Intra
GORASP2 Q9H8Y8 DPYSL2 Homo sapiens Q16555 29892012
Intra
GORASP2 Q9H8Y8 DPYSL2 Homo sapiens Q16555 32296183
Intra
GORASP2 Q9H8Y8 MPLKIP Homo sapiens Q8TAP9 32296183
Intra
GORASP2 Q9H8Y8 TLE5 Homo sapiens Q08117-2 32296183
Intra
GORASP2 Q9H8Y8 TLE5 Homo sapiens Q08117-2 32296183
Intra
GORASP2 Q9H8Y8 ZNF148 Homo sapiens Q9UQR1-2 32296183
Intra
GORASP2 Q9H8Y8 TSC22D1 Homo sapiens Q15714-2 32296183
Intra
GORASP2 Q9H8Y8 TSC22D1 Homo sapiens Q15714-2 32296183
Intra
GORASP2 Q9H8Y8 MATN4 Homo sapiens O95460-2 32296183
Intra
GORASP2 Q9H8Y8 MATN4 Homo sapiens O95460-2 32296183
Intra
GORASP2 Q9H8Y8 XPNPEP1 Homo sapiens Q9NQW7-3 32296183
Intra
GORASP2 Q9H8Y8 EURL Homo sapiens Q9NYK6-3 32296183
Intra
GORASP2 Q9H8Y8 KIFC3 Homo sapiens Q9BVG8-5 32296183
Intra
GORASP2 Q9H8Y8 KIFC3 Homo sapiens Q9BVG8-5 32296183
Intra
GORASP2 Q9H8Y8 KIFC3 Homo sapiens Q9BVG8 25416956
Intra
GORASP2 Q9H8Y8 KIFC3 Homo sapiens Q9BVG8 25416956
Intra
GORASP2 Q9H8Y8 KIFC3 Homo sapiens Q9BVG8 25416956
Intra
GORASP2 Q9H8Y8 TRIM38 Homo sapiens O00635 32296183
Intra
GORASP2 Q9H8Y8 TRIM38 Homo sapiens O00635 32296183
Intra
GORASP2 Q9H8Y8 TRIM38 Homo sapiens O00635 25416956
Intra
GORASP2 Q9H8Y8 TRIM38 Homo sapiens O00635 25416956
Intra
GORASP2 Q9H8Y8 LONRF1 Homo sapiens Q17RB8 25416956
Intra
GORASP2 Q9H8Y8 LONRF1 Homo sapiens Q17RB8 25416956
Intra
GORASP2 Q9H8Y8 LONRF1 Homo sapiens Q17RB8 32296183
Intra
GORASP2 Q9H8Y8 BLZF1 Homo sapiens Q9H2G9 33961781
Intra
GORASP2 Q9H8Y8 BLZF1 Homo sapiens Q9H2G9
Y2H
21988832
Intra
GORASP2 Q9H8Y8 BLZF1 Homo sapiens Q9H2G9 35271311
Intra
GORASP2 Q9H8Y8 ZNF148 Homo sapiens Q9UQR1 25416956
Intra
GORASP2 Q9H8Y8 VPS52 Homo sapiens Q8N1B4 32296183
Intra
GORASP2 Q9H8Y8 VPS52 Homo sapiens Q8N1B4 32296183
Intra
GORASP2 Q9H8Y8 ECHDC1 Homo sapiens Q9NTX5 32296183
Intra
GORASP2 Q9H8Y8 CNTNAP2 Homo sapiens Q9UHC6 32296183
Intra
GORASP2 Q9H8Y8 BTBD3 Homo sapiens Q9Y2F9 32296183
Intra
GORASP2 Q9H8Y8 BTBD3 Homo sapiens Q9Y2F9 32296183
Intra
GORASP2 Q9H8Y8 BTBD3 Homo sapiens Q9Y2F9 32296183
Intra
GORASP2 Q9H8Y8 EMILIN3 Homo sapiens Q9NT22 32296183
Intra
GORASP2 Q9H8Y8 PSMA3 Homo sapiens P25788 25416956
Intra
GORASP2 Q9H8Y8 CFTR Homo sapiens P13569 21884936
Intra
GORASP2 Q9H8Y8 TRAF2 Homo sapiens Q12933 25416956
Intra
GORASP2 Q9H8Y8 TRAF2 Homo sapiens Q12933 32296183
Intra
GORASP2 Q9H8Y8 TRAF2 Homo sapiens Q12933 32296183
Intra
GORASP2 Q9H8Y8 PSMD2 Homo sapiens Q13200 32814053
Intra
GORASP2 Q9H8Y8 PSMD2 Homo sapiens Q13200 32814053
Intra
GORASP2 Q9H8Y8 PSMD2 Homo sapiens Q13200 32814053
Intra
GORASP2 Q9H8Y8 NQO2 Homo sapiens P16083 32296183
Intra
GORASP2 Q9H8Y8 NQO2 Homo sapiens P16083 32296183
Intra
GORASP2 Q9H8Y8 TRAF1 Homo sapiens Q13077 25416956
Intra
GORASP2 Q9H8Y8 TRAF1 Homo sapiens Q13077 25416956
Intra
GORASP2 Q9H8Y8 TRAF1 Homo sapiens Q13077 32296183
Intra
GORASP2 Q9H8Y8 TRAF1 Homo sapiens Q13077 25416956
Intra
GORASP2 Q9H8Y8 TRAF1 Homo sapiens Q13077 32296183
Intra
GORASP2 Q9H8Y8 APIP Homo sapiens Q96GX9 32296183
Intra
GORASP2 Q9H8Y8 APIP Homo sapiens Q96GX9 32296183
Intra
GORASP2 Q9H8Y8 TXLNA Homo sapiens P40222 25416956
Intra
GORASP2 Q9H8Y8 TXLNA Homo sapiens P40222 32296183
Intra
GORASP2 Q9H8Y8 TXLNA Homo sapiens P40222 25416956
Intra
GORASP2 Q9H8Y8 TXLNA Homo sapiens P40222 25416956
Intra
GORASP2 Q9H8Y8 TXLNA Homo sapiens P40222 32296183
Intra
GORASP2 Q9H8Y8 TRAF4 Homo sapiens Q9BUZ4 25416956
Intra
GORASP2 Q9H8Y8 GTF2IRD1 Homo sapiens Q9UHL9 32296183
Intra
GORASP2 Q9H8Y8 MAP1LC3B Homo sapiens Q9GZQ8 25416956
Intra
GORASP2 Q9H8Y8 ACY3 Homo sapiens Q96HD9 25416956
Intra
GORASP2 Q9H8Y8 ACY3 Homo sapiens Q96HD9 32296183
Intra
GORASP2 Q9H8Y8 ACY3 Homo sapiens Q96HD9 31515488
Intra
GORASP2 Q9H8Y8 ACY3 Homo sapiens Q96HD9 25416956
Intra
GORASP2 Q9H8Y8 ACY3 Homo sapiens Q96HD9 32296183
Intra
GORASP2 Q9H8Y8 NMNAT1 Homo sapiens Q9HAN9 32296183
Intra
GORASP2 Q9H8Y8 STOX1 Homo sapiens Q6ZVD7 25416956
Intra
GORASP2 Q9H8Y8 CDC23 Homo sapiens Q9UJX2 25416956
Intra
GORASP2 Q9H8Y8 CDC23 Homo sapiens Q9UJX2 32296183
Intra
GORASP2 Q9H8Y8 CDC23 Homo sapiens Q9UJX2 32296183
Intra
GORASP2 Q9H8Y8 CDC23 Homo sapiens Q9UJX2 32296183
Intra
GORASP2 Q9H8Y8 KCTD9 Homo sapiens Q7L273 32296183
Intra
GORASP2 Q9H8Y8 KCTD9 Homo sapiens Q7L273 25416956
Intra
GORASP2 Q9H8Y8 KCTD9 Homo sapiens Q7L273 32296183
Intra
GORASP2 Q9H8Y8 KCTD9 Homo sapiens Q7L273 25416956
Intra
GORASP2 Q9H8Y8 VPS37B Homo sapiens Q9H9H4 32296183
Intra
GORASP2 Q9H8Y8 VPS37B Homo sapiens Q9H9H4 32296183
Intra
GORASP2 Q9H8Y8 VPS37B Homo sapiens Q9H9H4 32296183
Intra
GORASP2 Q9H8Y8 EIF2B1 Homo sapiens Q14232 25416956
Intra
GORASP2 Q9H8Y8 EIF2B1 Homo sapiens Q14232 25416956
Intra
GORASP2 Q9H8Y8 EIF2B1 Homo sapiens Q14232 32296183
Intra
GORASP2 Q9H8Y8 EIF2B1 Homo sapiens Q14232 25416956
Intra
GORASP2 Q9H8Y8 EIF2B1 Homo sapiens Q14232 32296183
Intra
GORASP2 Q9H8Y8 TRAF5 Homo sapiens O00463 25416956
Intra
GORASP2 Q9H8Y8 TRAF5 Homo sapiens O00463 25416956
Intra
GORASP2 Q9H8Y8 GOLGA2 Homo sapiens Q08379 25416956
Intra
GORASP2 Q9H8Y8 GOLGA2 Homo sapiens Q08379 33961781
Intra
GORASP2 Q9H8Y8 GOLGA2 Homo sapiens Q08379 25416956
Intra
GORASP2 Q9H8Y8 GOLGA2 Homo sapiens Q08379
Y2H
21900206
Intra
GORASP2 Q9H8Y8 GOLGA2 Homo sapiens Q08379 35271311
Intra
GORASP2 Q9H8Y8 GOLGA2 Homo sapiens Q08379 25416956
Intra
GORASP2 Q9H8Y8 CRYAA Homo sapiens P02489 25416956
Intra
GORASP2 Q9H8Y8 CRYAA Homo sapiens P02489 25416956
Intra
GORASP2 Q9H8Y8 CRYAA Homo sapiens P02489 32296183
Intra
GORASP2 Q9H8Y8 CRYAA Homo sapiens P02489 25416956
Intra
GORASP2 Q9H8Y8 CRYAA Homo sapiens P02489 32296183
Intra
GORASP2 Q9H8Y8 ENOX1 Homo sapiens Q8TC92 25416956
Intra
GORASP2 Q9H8Y8 SHMT1 Homo sapiens P34896 32296183
Intra
GORASP2 Q9H8Y8 SHMT1 Homo sapiens P34896 32296183
Intra
GORASP2 Q9H8Y8 GNG7 Homo sapiens O60262 32296183
Intra
GORASP2 Q9H8Y8 CARHSP1 Homo sapiens Q9Y2V2 32296183
Intra
GORASP2 Q9H8Y8 NUDT5 Homo sapiens Q9UKK9 32296183
Intra
GORASP2 Q9H8Y8 CGGBP1 Homo sapiens Q9UFW8 32296183
Intra
GORASP2 Q9H8Y8 BEND5 Homo sapiens Q7L4P6 25416956
Intra
GORASP2 Q9H8Y8 BEND5 Homo sapiens Q7L4P6 25416956
Intra
GORASP2 Q9H8Y8 MORN2 Homo sapiens Q502X0 25416956
Intra
GORASP2 Q9H8Y8 MORN2 Homo sapiens Q502X0 25416956
Intra
GORASP2 Q9H8Y8 DUSP21 Homo sapiens Q9H596 25416956
Intra
GORASP2 Q9H8Y8 DUSP21 Homo sapiens Q9H596 25416956
Intra
GORASP2 Q9H8Y8 DUSP21 Homo sapiens Q9H596 31515488
Intra
GORASP2 Q9H8Y8 CRYAB Homo sapiens P02511 32296183
Intra
GORASP2 Q9H8Y8 CRYAB Homo sapiens P02511 32296183
Intra
GORASP2 Q9H8Y8 DCTD Homo sapiens P32321 32296183
Intra
GORASP2 Q9H8Y8 DCTD Homo sapiens P32321 32296183
Intra
GORASP2 Q9H8Y8 ZBED1 Homo sapiens O96006 32296183
Intra
GORASP2 Q9H8Y8 ZBED1 Homo sapiens O96006 32296183
Intra
GORASP2 Q9H8Y8 PCBD1 Homo sapiens P61457 32296183
Intra
GORASP2 Q9H8Y8 PCBD1 Homo sapiens P61457 32296183
Intra
GORASP2 Q9H8Y8 CEP76 Homo sapiens Q8TAP6 32296183
Intra
GORASP2 Q9H8Y8 CEP76 Homo sapiens Q8TAP6 32296183
Intra
GORASP2 Q9H8Y8 KCTD13 Homo sapiens Q8WZ19 32296183
Intra
GORASP2 Q9H8Y8 KCTD13 Homo sapiens Q8WZ19 32296183
Intra
GORASP2 Q9H8Y8 CBLB Homo sapiens Q13191 25416956
Intra
GORASP2 Q9H8Y8 CBLB Homo sapiens Q13191 31515488
Intra
GORASP2 Q9H8Y8 CBLB Homo sapiens Q13191 25416956
Intra
GORASP2 Q9H8Y8 CBLB Homo sapiens Q13191 32296183
Intra
GORASP2 Q9H8Y8 CBLB Homo sapiens Q13191 32296183
Intra
GORASP2 Q9H8Y8 CBLB Homo sapiens Q13191 25416956
Intra
GORASP2 Q9H8Y8 RPIA Homo sapiens P49247 25416956
Intra
GORASP2 Q9H8Y8 RPIA Homo sapiens P49247 32296183
Intra
GORASP2 Q9H8Y8 RPIA Homo sapiens P49247 32296183
Intra
GORASP2 Q9H8Y8 SCAND1 Homo sapiens P57086 25416956
Intra
GORASP2 Q9H8Y8 SCAND1 Homo sapiens P57086 25416956
Intra
GORASP2 Q9H8Y8 IFT25 Homo sapiens Q9Y547 32296183
Intra
GORASP2 Q9H8Y8 PRDX3 Homo sapiens P30048 31515488
Intra
GORASP2 Q9H8Y8 PRDX3 Homo sapiens P30048 25416956
Intra
GORASP2 Q9H8Y8 PRPS1 Homo sapiens P60891 31515488
Intra
GORASP2 Q9H8Y8 PRPS1 Homo sapiens P60891 32296183
Intra
GORASP2 Q9H8Y8 PRPS1 Homo sapiens P60891 32296183
Intra
GORASP2 Q9H8Y8 GABPB2 Homo sapiens Q8TAK5 25416956
Intra
GORASP2 Q9H8Y8 GABPB2 Homo sapiens Q8TAK5 32296183
Intra
GORASP2 Q9H8Y8 GABPB2 Homo sapiens Q8TAK5 32296183
Intra
GORASP2 Q9H8Y8 ALKBH4 Homo sapiens Q9NXW9 32296183
Intra
GORASP2 Q9H8Y8 TEKT3 Homo sapiens Q9BXF9
Y2H
21516116
Intra
GORASP2 Q9H8Y8 TEKT3 Homo sapiens Q9BXF9 25416956
Intra
GORASP2 Q9H8Y8 CSNK1D Homo sapiens P48730-2 32814053
Intra
GORASP2 Q9H8Y8 CSNK1D Homo sapiens P48730-2 32814053
Intra
GORASP2 Q9H8Y8 CSNK1D Homo sapiens P48730-2 32814053
Intra
GORASP2 Q9H8Y8 CDA Homo sapiens P32320 32296183
Intra
GORASP2 Q9H8Y8 CDA Homo sapiens P32320 32296183
Intra
GORASP2 Q9H8Y8 DMC1 Homo sapiens Q14565 25416956
Intra
GORASP2 Q9H8Y8 DMC1 Homo sapiens Q14565 31515488
Intra
GORASP2 Q9H8Y8 DMC1 Homo sapiens Q14565 25416956
Intra
GORASP2 Q9H8Y8 C1orf94 Homo sapiens Q6P1W5 32296183
Intra
GORASP2 Q9H8Y8 C1orf94 Homo sapiens Q6P1W5 25416956
Intra
GORASP2 Q9H8Y8 C1orf94 Homo sapiens Q6P1W5 32296183
Intra
GORASP2 Q9H8Y8 C1orf94 Homo sapiens Q6P1W5 25416956
Intra
GORASP2 Q9H8Y8 CBY1 Homo sapiens Q9Y3M2 32296183
Intra
GORASP2 Q9H8Y8 CBY1 Homo sapiens Q9Y3M2 32296183
Intra
GORASP2 Q9H8Y8 CBY1 Homo sapiens Q9Y3M2 32296183
Cross
GORASP2 Q9H8Y8 Q99IB8-PRO_0000045603 Hepatitis C virus Q99IB8-PRO_0000045603 24136289
Cross
GORASP2 Q9H8Y8 Q99IB8-PRO_0000045603 Hepatitis C virus Q99IB8-PRO_0000045603
Y2H
24136289
Cross
GORASP2 Q9H8Y8 Q99IB8-PRO_0000045603 Hepatitis C virus Q99IB8-PRO_0000045603 24136289
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Smith-Mccort Dysplasia 1

Smith-Mccort Dysplasia

SMC1

Smc

Smith Mccort Dysplasia

Smith-Mccort Dwarfism

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus GORASP2 MGD MGI:2135962
Macaca mulatta GORASP2 VGNC VGNC:72957
Felis catus GORASP2 VGNC VGNC:62648
Bos taurus GORASP2 VGNC VGNC:29499
Rattus norvegicus GORASP2 RGD RGD:619911
Canis familiaris GORASP2 VGNC VGNC:41352