1. Gene
  2. CDC26 - cell division cycle 26 Gene

CDC26 - cell division cycle 26 Gene

Homo sapiens

Also known as APC12; ANAPC12; C9orf17

Gene ID: 246184 | Gene type: protein coding

About CDC26

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:113,266,992-113,275,572 (from NCBI)

This gene has 2 transcripts (splice variants) and 176 orthologues. Ubiquitous expression in kidney (RPKM 9.9), appendix (RPKM 9.9) and 25 other tissues.

Summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein Ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. [provided by RefSeq, Jul 2008]

CDC26 Products(1)

mRNA Protein Name
NM_139286.4 NP_644815.1 anaphase-promoting complex subunit CDC26

CDC26 Protein Structure

ANAPC_CDC26

ANAPC_CDC26: Anaphase-promoting complex APC subunit CDC26 (1 - 57)

  • 0
  • 85 a.a.
Protein Preferred Names Protein Names

anaphase-promoting complex subunit CDC26

CDC26 subunit of anaphase promoting complex

Related Diseases

Diseases Alias
Retinitis Pigmentosa 27

RP27

Retinal Degeneration, Autosomal Recessive, Clumped Pigment Type

Retinal Degeneration Autosomal Recessive Clumped Pigment Type

RDCP

Clumped Pigmentary Retinal Degeneration

Retinitis Pigmentosa, Type 27

Cornea Cancer

Malignant Neoplasm Of Cornea

Neoplasm Of Cornea

Corneal Tumor

Malignant Corneal Tumor

Malignant Tumor Of Cornea

Primary Malignant Neoplasm Of Cornea

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris CDC26 VGNC VGNC:38992
Bos taurus CDC26 VGNC VGNC:27065
Felis catus CDC26 VGNC VGNC:60652
Mus musculus CDC26 MGD MGI:1913690
Macaca mulatta CDC26 VGNC VGNC:70817
Rattus norvegicus CDC26 RGD RGD:1311342