2. Gene
  3. EPGN - epithelial mitogen Gene

EPGN - epithelial mitogen Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as EPG; PRO9904; ALGV3072

Gene ID: 255324 | Gene type: protein coding

About EPGN

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:74,308,470-74,316,789 (from NCBI)

This gene has 9 transcripts (splice variants), 110 orthologues and 5 paralogues. Restricted expression toward esophagus (RPKM 11.2).

Summary

The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in Cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

EPGN Products(6)

mRNA Protein Name
NM_001013442.2 NP_001013460.1 epigen isoform 6 precursor
NM_001270989.2 NP_001257918.1 epigen isoform 1 precursor
NM_001270990.2 NP_001257919.1 epigen isoform 2 precursor
NM_001270991.2 NP_001257920.1 epigen isoform 3 precursor
NM_001270992.2 NP_001257921.1 epigen isoform 4 precursor
NM_001270993.2 NP_001257922.1 epigen isoform 5 precursor
Protein Preferred Names Protein Names

epigen

epithelial mitogen homolog

Recombinant EPGN Proteins

Cat. No. Product Name Accession Purity
HY-P7010 Epigen Protein, Human Q6UW88-2 (A24-A95) ≥95%
HY-P7010A Epigen Protein, Human (CHO) Q6UW88-2 (A24-A104) ≥95%

Related Diseases

Diseases Alias
Vallecula Cancer

Malignant Tumor Of Vallecula
Bronchiectasis 2
Proliferative Glomerulonephritis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04423 EPGN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EPGN RGD RGD:1560084
Bos taurus EPGN VGNC VGNC:53711
Felis catus EPGN VGNC VGNC:107331
Mus musculus EPGN MGD MGI:1919170
Canis familiaris EPGN VGNC VGNC:40403
Macaca mulatta EPGN VGNC VGNC:72061