2. Gene
  3. PGLS - 6-phosphogluconolactonase Gene

PGLS - 6-phosphogluconolactonase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as 6PGL; HEL-S-304

Gene ID: 25796 | Gene type: protein coding

About PGLS

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,511,649-17,521,288 (from NCBI)

This gene has 6 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in spleen (RPKM 10.2), colon (RPKM 9.1) and 25 other tissues.

Summary

Enables 6-phosphogluconolactonase activity. Involved in pentose-phosphate shunt. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PGLS Products(1)

mRNA Protein Name
NM_012088.3 NP_036220.1 6-phosphogluconolactonase

PGLS Protein Structure

Glucosamine_iso

Glucosamine_iso: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase (20 - 216)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

6-phosphogluconolactonase

epididymis secretory protein Li 304

PGLS Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
PGLS O95336 BLMH Homo sapiens Q13867
Y2H Array
32296183
Intra
PGLS O95336 BLMH Homo sapiens Q13867
Validated Y2H
32296183
Intra
PGLS O95336 TERF2IP Homo sapiens Q9NYB0
BiFC
21044950
Intra
PGLS O95336 TERF2IP Homo sapiens Q9NYB0
Pull Down
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-123148 IMB-808 Agonist 99.85% Unkown
HY-139691 SR15006 Inhibitor 99.95% Unkown
HY-113736 Glycyllysine / Unkown
HY-RS10386 PGLS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PGLS RGD RGD:1307001
Macaca mulatta PGLS VGNC VGNC:75967
Canis familiaris PGLS VGNC VGNC:44460
Felis catus PGLS VGNC VGNC:80652
Bos taurus PGLS VGNC VGNC:32790
Mus musculus PGLS MGD MGI:1913421